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Dosimetric Comparison of CPAP and DIBH for Left-sided Breast Cancer Radiation Therapy

Authors
 Min Seo Choi  ;  Ryeong Hwang Park  ;  Joongyo Lee  ;  Yeona Cho  ;  Jee Suk Chang  ;  Jihun Kim  ;  Jin Sung Kim 
Citation
 ADVANCES IN RADIATION ONCOLOGY, Vol.9(6) : 101478, 2024-06 
Journal Title
ADVANCES IN RADIATION ONCOLOGY
Issue Date
2024-06
Abstract
Purpose: Despite the increasing interest in using continuous positive airway pressure (CPAP) in radiation therapy (RT), direct comparisons with the more widely used deep inspiration breath-hold (DIBH) have been limited. This planning study aimed to offer comprehensive geometric and dosimetric evidence by comparing CPAP and DIBH-based RT plans. Materials and Methods: A retrospective data set of 35 patients with left-sided breast cancer with planning computed tomography scans under three breathing conditions (free breathing (FB), CPAP with 10 cmH2O pressure, and DIBH) was collected. Volumetric arc therapy plans aimed for 95% dose coverage to 95% of the planning target volume with a maximum dose below 107%. A comparative dosimetric analysis among the three plans was conducted. Additionally, geometric differences were assessed by calculating the minimum distance between the heart and the clinical target volume (CTV) in each planning computed tomography. Results: CPAP and DIBH plans demonstrated comparable mean heart doses (1.05 Gy), which were significantly lower than the FB plan (1.34 Gy). The maximum dose to the left anterior descending artery was smallest in the CPAP plan (4.44 Gy), followed by DIBH (4.73 Gy) and FB (7.33 Gy) plans. Other organ-at-risk doses for CPAP and DIBH were similar, with mean contralateral breast doses of 2.27 and 2.21 Gy, mean ipsilateral lung doses of 4.09 and 4.08 Gy, V20 at 6.11% and 6.31%, and mean contralateral lung doses of 0.94 and 0.92 Gy, respectively. No significant difference was found in the minimum heart-to-CTV distance between CPAP and DIBH. DIBH exhibited the greatest lung volume (3908 cc), followed by CPAP (3509 cc), and FB(2703 cc). Conclusions: The comparison between CPAP and DIBH shows their similarity in both geometric and dosimetric aspects, providing strong evidence for CPAP's effectiveness and feasibility in RT. This suggests its potential as an alternative to DIBH for patients with left-sided breast cancer. © 2024 The Author(s)
Files in This Item:
T202403261.pdf Download
DOI
10.1016/j.adro.2024.101478
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jihun(김지훈) ORCID logo https://orcid.org/0000-0003-4856-6305
Kim, Jinsung(김진성) ORCID logo https://orcid.org/0000-0003-1415-6471
Lee, Joongyo(이준교)
Chang, Jee Suk(장지석) ORCID logo https://orcid.org/0000-0001-7685-3382
Cho, Yeona(조연아) ORCID logo https://orcid.org/0000-0002-1202-0880
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/199708
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