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Clinical Practice Guideline for Blood-based Circulating Tumor DNA Assays

Authors
 Jee-Soo Lee  ;  Eun Hye Cho  ;  Boram Kim  ;  Jinyoung Hong  ;  Young-Gon Kim  ;  Yoonjung Kim  ;  Ja-Hyun Jang  ;  Seung-Tae Lee  ;  Sun-Young Kong  ;  Woochang Lee  ;  Saeam Shin  ;  Eun Young Song  ;  Clinical Practice Guidelines Committee of the Korean Society for Laboratory Medicine 
Citation
 ANNALS OF LABORATORY MEDICINE, Vol.44(3) : 195-209, 2024-05 
Journal Title
ANNALS OF LABORATORY MEDICINE
ISSN
 2234-3806 
Issue Date
2024-05
MeSH
Biomarkers, Tumor / genetics ; Circulating Tumor DNA* / genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation ; Neoplasm, Residual / genetics ; Prognosis
Keywords
Cell-free nucleic acid ; Circulating tumor DNA ; Guideline ; High-throughput nucleotide sequencing
Abstract
Circulating tumor DNA (ctDNA) has emerged as a promising tool for various clinical applications, including early diagnosis, therapeutic target identification, treatment response monitoring, prognosis evaluation, and minimal residual disease detection. Consequently, ctDNA assays have been incorporated into clinical practice. In this review, we offer an in-depth exploration of the clinical implementation of ctDNA assays. Notably, we examined existing evidence related to pre-analytical procedures, analytical components in current technologies, and result interpretation and reporting processes. The primary objective of this guidelines is to provide recommendations for the clinical utilization of ctDNA assays.
Files in This Item:
T202401499.pdf Download
DOI
10.3343/alm.2023.0389
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Shin, Saeam(신새암) ORCID logo https://orcid.org/0000-0003-1501-3923
Lee, Seung-Tae(이승태) ORCID logo https://orcid.org/0000-0003-1047-1415
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/198696
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