0 60

Cited 2 times in

Interobserver Variability and Diagnostic Performance in Predicting Malignancy of Pancreatic Intraductal Papillary Mucinous Neoplasm with MRI

DC Field Value Language
dc.contributor.author김연윤-
dc.date.accessioned2024-03-22T06:02:20Z-
dc.date.available2024-03-22T06:02:20Z-
dc.date.issued2023-07-
dc.identifier.issn0033-8419-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/198350-
dc.description.abstractBackground The 2017 international consensus guidelines for intraductal papillary mucinous neoplasm (IPMN) of the pancreas are widely used. Purpose To evaluate the interobserver agreement and diagnostic performance of MRI assessment in predicting the malignant potential of IPMN according to radiologists' experience. Materials and Methods This multicenter retrospective study included 100 patients with pathologically proven pancreatic IPMN (77 patients with surgery, 23 patients with biopsy) who underwent contrast-enhanced MRI between 2016 and 2021. Eight post-fellowship radiologists (four more-experienced [8-20 years] and four less-experienced [1-4 years] reviewers) evaluated MRI for high-risk stigmata and worrisome features identified by the most recent 2017 guidelines. Interobserver agreement was determined using Fleiss κ statistics according to radiologist experience. The diagnostic performance for malignant IPMN was assessed using receiver operating characteristic curve analysis. Results Among 100 patients (mean age, 66 years ± 10 [SD]; 57 men), 52 (52%) had malignant IPMN. For high-risk stigmata, interobserver agreement was substantial for main pancreatic duct size of at least 10 mm (κ = 0.78; 95% CI: 0.75, 0.82), enhancing mural nodule of at least 5 mm (κ = 0.70: 95% CI: 0.66, 0.74), and at least one high-risk stigmata (κ = 0.73: 95% CI: 0.69, 0.76). The worrisome features showed fair to substantial interobserver agreement (κ range, 0.22-0.80). More-experienced reviewers demonstrated better agreement in the assessment of at least one high-risk stigmata than less-experienced reviewers (κ = 0.77 vs κ = 0.69, P < .001). The overall diagnostic performance of each reviewer was good for the prediction of malignant pancreatic IPMN (area under the receiver operating characteristic curve [AUC] range, 0.77-0.84; median AUC, 0.82), with substantial agreement (κ = 0.76). Conclusion The 2017 international consensus guidelines enabled good diagnostic performance and substantial interobserver agreement for high-risk stigmata but not worrisome features on the evaluation of the malignant pancreatic IPMN using MRI. Agreement tended to be better among more-experienced reviewers than among less-experienced reviewers. © RSNA, 2023 Supplemental material is available for this article.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherRadiological Society of North America-
dc.relation.isPartOfRADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging-
dc.subject.MESHMale-
dc.subject.MESHObserver Variation-
dc.subject.MESHPancreatic Intraductal Neoplasms*-
dc.subject.MESHPancreatic Neoplasms*-
dc.subject.MESHRetrospective Studies-
dc.titleInterobserver Variability and Diagnostic Performance in Predicting Malignancy of Pancreatic Intraductal Papillary Mucinous Neoplasm with MRI-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorSeo-Youn Choi-
dc.contributor.googleauthorJi Hye Min-
dc.contributor.googleauthorJung Hoon Kim-
dc.contributor.googleauthorHyun Jeong Park-
dc.contributor.googleauthorYeun-Yoon Kim-
dc.contributor.googleauthorYeo Eun Han-
dc.contributor.googleauthorSung Hwan Bae-
dc.contributor.googleauthorJeong Hyun Lee-
dc.contributor.googleauthorYoon-Hyeong Choi-
dc.contributor.googleauthorJi Eun Moon-
dc.identifier.doi10.1148/radiol.222463-
dc.contributor.localIdA04902-
dc.relation.journalcodeJ02596-
dc.identifier.eissn1527-1315-
dc.identifier.pmid37489989-
dc.identifier.urlhttps://pubs.rsna.org/doi/10.1148/radiol.222463-
dc.contributor.alternativeNameKim, Yeun-Yoon-
dc.contributor.affiliatedAuthor김연윤-
dc.citation.volume308-
dc.citation.number1-
dc.citation.startPagee222463-
dc.identifier.bibliographicCitationRADIOLOGY, Vol.308(1) : e222463, 2023-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.