Cited 2 times in
Comparison of Coronary Computed Tomography Angiography Image Quality With High-concentration and Low-concentration Contrast Agents: The Randomized CONCENTRATE Trial
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최병욱 | - |
dc.contributor.author | 임동진 | - |
dc.contributor.author | 한경화 | - |
dc.date.accessioned | 2024-03-22T05:49:32Z | - |
dc.date.available | 2024-03-22T05:49:32Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.issn | 0883-5993 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198230 | - |
dc.description.abstract | Purpose:To confirm that the image quality of coronary computed tomography (CT) angiography with a low tube voltage (80 to 100 kVp), iterative reconstruction, and low-concentration contrast agents (iodixanol 270 to 320 mgI/mL) was not inferior to that with conventional high tube voltage (120 kVp) and high-concentration contrast agent (iopamidol 370 mgI/mL). Materials and Methods:This prospective, multicenter, noninferiority, randomized trial enrolled a total of 318 patients from 8 clinical sites. All patients were randomly assigned 1: 1: 1 for each contrast medium of 270, 320, and 370 mgI/mL. CT scans were taken with a standard protocol in the high-concentration group (370 mgI/mL) and with 20 kVp lower protocol in the low-concentration group (270 or 320 mgI/mL). Image quality and radiation dose were compared between the groups. Image quality was evaluated with a score of 1 to 4 as subject image quality. Results:The mean HU, signal-to-noise ratio, and contrast-to-noise ratio of the 3 groups were significantly different (all P<0.0001). The signal-to-noise ratio and contrast-to-noise ratio of the low-concentration groups were significantly lower than those of the high-concentration group (P<0.05). However, the image quality scores were not significantly different among the 3 groups (P=0.745). The dose length product and effective dose of the high-concentration group were significantly higher than those of the low-concentration group (P<0.0001 and 0.003, respectively). Conclusions:The CT protocol with iterative reconstruction and lower tube voltage for low-concentration contrast agents significantly reduced the effective radiation dose (mean: 3.7 +/- 2.7 to 4.1 +/- 3.1 mSv) while keeping the subjective image quality as good as the standard protocol (mean: 5.7 +/- 3.4 mSv). | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | JOURNAL OF THORACIC IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Computed Tomography Angiography* | - |
dc.subject.MESH | Contrast Media* | - |
dc.subject.MESH | Coronary Angiography / methods | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Radiation Dosage | - |
dc.subject.MESH | Radiographic Image Interpretation, Computer-Assisted / methods | - |
dc.subject.MESH | Tomography, X-Ray Computed / methods | - |
dc.title | Comparison of Coronary Computed Tomography Angiography Image Quality With High-concentration and Low-concentration Contrast Agents: The Randomized CONCENTRATE Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Dong Jin Im | - |
dc.contributor.googleauthor | Yun-Hyeon Kim | - |
dc.contributor.googleauthor | Ki Seok Choo | - |
dc.contributor.googleauthor | Joon-Won Kang | - |
dc.contributor.googleauthor | Jung Im Jung | - |
dc.contributor.googleauthor | Yoodong Won | - |
dc.contributor.googleauthor | Hyo Rim Kim | - |
dc.contributor.googleauthor | Myung Hee Chung | - |
dc.contributor.googleauthor | Kyunghwa Han | - |
dc.contributor.googleauthor | Byoung Wook Choi | - |
dc.identifier.doi | 10.1097/RTI.0000000000000633 | - |
dc.contributor.localId | A04059 | - |
dc.relation.journalcode | J01908 | - |
dc.identifier.eissn | 1536-0237 | - |
dc.identifier.pmid | 36821380 | - |
dc.identifier.url | https://journals.lww.com/thoracicimaging/fulltext/2023/03000/comparison_of_coronary_computed_tomography.7.aspx | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | 최병욱 | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 120 | - |
dc.citation.endPage | 127 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THORACIC IMAGING, Vol.38(2) : 120-127, 2023-03 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.