Cited 0 times in
Association between waist circumference trajectories and incident non-alcoholic fatty liver disease
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권유진 | - |
dc.contributor.author | 이혜선 | - |
dc.date.accessioned | 2023-11-28T03:26:44Z | - |
dc.date.available | 2023-11-28T03:26:44Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.issn | 1871-403X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196810 | - |
dc.description.abstract | Purpose: Waist circumference (WC) is linked to non-alcoholic fatty liver disease (NAFLD) incidence. However, the impact of longitudinal WC changes on NAFLD remains unclear. We investigated WC trajectories and NAFLD incidence in a large population-based cohort. Methods: We analyzed data from 2666 participants without NAFLD, who underwent biennial check-ups for 16 years, divided into a 6-year exposure period and a 10-year event accrual period. Participants were classified into increasing and decreasing WC trajectory groups during the median 5.9-year exposure period by group-based trajectory modeling. Multiple Cox proportional hazard regression analysis estimated the hazard ratio (HR) and 95 % confidence interval (CI) for incident NAFLD. Results: During the median 9.7-year event accrual period, 799 participants developed NAFLD. The increasing WC trajectory group had a higher NAFLD risk than the decreasing group, with an HR of 1.20 (95 % CI: 1.02-1.42). After adjusting for confounders, the adjusted-HR was 1.28 (95 % CI: 1.07-1.53). Subgroup analyses revealed significant findings for groups, regardless of abdominal obesity status. Conclusion: An increasing WC trend was associated with a higher NAFLD risk, independent of abdominal obesity status. Monitoring WC changes may facilitate early detection of NAFLD risk groups and promote lifestyle modifications to prevent NAFLD onset. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | OBESITY RESEARCH & CLINICAL PRACTICE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Non-alcoholic Fatty Liver Disease* / epidemiology | - |
dc.subject.MESH | Non-alcoholic Fatty Liver Disease* / etiology | - |
dc.subject.MESH | Obesity, Abdominal / complications | - |
dc.subject.MESH | Obesity, Abdominal / epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Waist Circumference | - |
dc.title | Association between waist circumference trajectories and incident non-alcoholic fatty liver disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Jun-Hyuk Lee | - |
dc.contributor.googleauthor | Soyoung Jeon | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Yu-Jin Kwon | - |
dc.identifier.doi | 10.1016/j.orcp.2023.09.005 | - |
dc.contributor.localId | A04882 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J02406 | - |
dc.identifier.pmid | 37704496 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1871403X23001060 | - |
dc.subject.keyword | Cohort | - |
dc.subject.keyword | Non-alcoholic fatty liver disease | - |
dc.subject.keyword | Trajectory analysis | - |
dc.subject.keyword | Waist circumference | - |
dc.contributor.alternativeName | Kwon, Yu-Jin | - |
dc.contributor.affiliatedAuthor | 권유진 | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.citation.volume | 17 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 398 | - |
dc.citation.endPage | 404 | - |
dc.identifier.bibliographicCitation | OBESITY RESEARCH & CLINICAL PRACTICE, Vol.17(5) : 398-404, 2023-10 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.