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Effect of High-Versus Low-Frequency of Abdominopelvic Computed Tomography Follow-Up Testing on Overall Survival in Patients With Stage II Or III Colon Cancer
DC Field | Value | Language |
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dc.contributor.author | 김한상 | - |
dc.contributor.author | 김현욱 | - |
dc.contributor.author | 신상준 | - |
dc.contributor.author | 안중배 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 장지석 | - |
dc.contributor.author | 한대훈 | - |
dc.contributor.author | 한윤대 | - |
dc.date.accessioned | 2023-11-28T03:06:38Z | - |
dc.date.available | 2023-11-28T03:06:38Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 1533-0028 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196733 | - |
dc.description.abstract | Background: Intensive surveillance of colon cancer by using the abdominopelvic computed tomography (AP-CT) is common in real world practice; however, it is still unclear whether high-frequency surveillance using AP-CT in patients with these risk factors is superior to that in the low-frequency surveillance. Patients and methods: We retrospectively reviewed 1803 patients with stage II-III colon cancer receiving curative surgery between January 1, 2005 to December 31, 2015. We evaluated the average scan-to-scan intervals of postoperative AP-CT testing and assigned patients with an interval of 5 to 8 and 9 to 13 months to the high-frequency (HF) and low-frequency (LF) groups, respectively. The cutoff value of preoperative and postoperative CEA levels was 5 ng/mL. We also applied propensity score matching (PSM) and inverse probability of treatment weighting to adjust clinicopathologic differences between the 2 groups. Results: We matched 1:1 for each surveillance group yielding a cohort of 776 matched patients. After PSM, Baseline demographics were overall well balanced between 2 groups. Stage III (OR, 2.00; 95% Confidence interval [CI], 1.21-3.30) and postoperative CEA elevation (OR, 2.30; 95% CI, 1.08-4.92) were independent risk factors of recurrence in multivariate analyses. Patient in the HF group had more surgery plus chemo- or radiotherapy as postrecurrence treatment than patient in the LF group (46.2% vs. 23.1%, P = .017). This trend was retained after PSM, although it is not significant (44.4% vs. 23.1%, P = .060). However, survival outcomes of high-frequency AP-CT surveillance were not superior to those of low-frequency surveillance in all subgroups, including stage III (HR 0.99, 95% CI 0.40-2.47) and postoperative CEA elevation (HR 1.36, 95% CI 0.45-4.11). Conclusion: High-frequency AP-CT testing is associated with a higher proportion of surgery plus chemo- or radiotherapy as postrecurrence treatment, without improvement in 6-year overall survival. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | CLINICAL COLORECTAL CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Colonic Neoplasms* / diagnostic imaging | - |
dc.subject.MESH | Colonic Neoplasms* / pathology | - |
dc.subject.MESH | Colonic Neoplasms* / therapy | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Effect of High-Versus Low-Frequency of Abdominopelvic Computed Tomography Follow-Up Testing on Overall Survival in Patients With Stage II Or III Colon Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jeongseok Jeon | - |
dc.contributor.googleauthor | Da Bin Lee | - |
dc.contributor.googleauthor | Sang Joon Shin | - |
dc.contributor.googleauthor | Dai Hoon Han | - |
dc.contributor.googleauthor | Jee Suk Chang | - |
dc.contributor.googleauthor | Yoon Dae Han | - |
dc.contributor.googleauthor | Hyunwook Kim | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Han Sang Kim | - |
dc.contributor.googleauthor | Joong Bae Ahn | - |
dc.identifier.doi | 10.1016/j.clcc.2023.05.003 | - |
dc.contributor.localId | A01098 | - |
dc.contributor.localId | A01126 | - |
dc.contributor.localId | A02105 | - |
dc.contributor.localId | A02262 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A04658 | - |
dc.contributor.localId | A04273 | - |
dc.contributor.localId | A04313 | - |
dc.relation.journalcode | J03468 | - |
dc.identifier.eissn | 1938-0674 | - |
dc.identifier.pmid | 37271592 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1533002823000488 | - |
dc.subject.keyword | Postoperative surveillance | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Recurrence | - |
dc.subject.keyword | Risk factor | - |
dc.subject.keyword | Surveillance | - |
dc.contributor.alternativeName | Kim, Han Sang | - |
dc.contributor.affiliatedAuthor | 김한상 | - |
dc.contributor.affiliatedAuthor | 김현욱 | - |
dc.contributor.affiliatedAuthor | 신상준 | - |
dc.contributor.affiliatedAuthor | 안중배 | - |
dc.contributor.affiliatedAuthor | 임준석 | - |
dc.contributor.affiliatedAuthor | 장지석 | - |
dc.contributor.affiliatedAuthor | 한대훈 | - |
dc.contributor.affiliatedAuthor | 한윤대 | - |
dc.citation.volume | 22 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 307 | - |
dc.citation.endPage | 317 | - |
dc.identifier.bibliographicCitation | CLINICAL COLORECTAL CANCER, Vol.22(3) : 307-317, 2023-09 | - |
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