Breast ; Biopsy ; Ultrasound guidance ; Breast cancer diagnosis
Abstract
Purpose: To determine the diagnostic accuracy, underestimation rate and false negative rate of
sonographically guided core needle biopsy for breast lesions.
Materials and Methods: We included 1,188 breast lesions from 1,020 patients who had undergone
sonographically guided 14-gauge core needle biopsies between January 2020 and December
2020. The sonographic BI-RADSⓇ category of breast lesions and the pathologic results of core
needle biopsies were reviewed and correlated with that of surgery or vacuum-assisted biopsy,
or >1year follow-up. The positive predictive value for each BI-RADSⓇ category, sensitivity,
underestimation rate and false negative rate of core needle biopsy were evaluated.
Results: Of the 1,188 core biopsy lesions, benign pathology was found in 46.0%, high-risk results
in 16.7%, and malignant results in 37.3%. The positive predictive values for each sonographic
category were as follows: 0.0% in category 3; 20.3% in category 4a; 75.8% in category 4b;
87.8% in category 4c and 95.9% in category 5. The sensitivity of core needle biopsy was 92.7%
(443/478). The underestimation rate was 16.2% (32/198) for high-risk and 33.3% (33/99) for
ductal carcinoma in situ. The false negative rate was 0.5% (3/547).
Conclusion: Sonographically guided core needle biopsy for 2020 year in our hospital was accurate
diagnostic tool for evaluating breast lesion