Cited 5 times in
O-RADS US: A Systematic Review and Meta-Analysis of Category-specific Malignancy Rates
DC Field | Value | Language |
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dc.contributor.author | 이선영 | - |
dc.date.accessioned | 2023-10-19T06:02:00Z | - |
dc.date.available | 2023-10-19T06:02:00Z | - |
dc.date.issued | 2023-08 | - |
dc.identifier.issn | 0033-8419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196330 | - |
dc.description.abstract | Background Ovarian-Adnexal Reporting and Data System (O-RADS) US provides a standardized method with which to stratify lesions into risk of malignancy categories, which is crucial for proper management. Purpose To perform a systematic review and meta-analysis to estimate malignancy rates for each O-RADS US score and evaluate the diagnostic performance of combined O-RADS US scores 4 and 5 in the diagnosis of malignancy. Materials and Methods A systematic literature search from the inception of the MEDLINE, EMBASE, and Web of Science databases through January 27, 2023, was performed for articles that reported using the O-RADS US stratification system and included malignancy rates per each O-RADS score. Bivariate random-effects models were used to determine the pooled malignancy rates for each O-RADS US score and to obtain summary estimates of the diagnostic performance of combined O-RADS US scores 4 and 5 in the diagnosis of malignant lesions. Results The final analysis included 18 studies consisting of 11 605 patients and 11 818 ovarian-adnexal lesions, with 2996 malignant (25.4%) and 8822 benign (74.6%) lesions. No malignant lesions were reported in O-RADS 1 category. The pooled percentages of malignancy were 0.6% (95% CI: 0.3, 1.0) for O-RADS 2, 3.9% (95% CI: 2.5, 5.4) for O-RADS 3, 43.5% (95% CI: 33.8, 53.2) for O-RADS 4, and 87.3% (95% CI: 83.0, 91.7) for O-RADS 5. The pooled sensitivity and specificity of combined O-RADS scores 4 and 5 in the diagnosis of malignant lesions were 95.6% (95% CI: 94.0, 97.2) and 76.6% (95% CI: 70.4, 82.7), respectively. Conclusion Each O-RADS US score provided the intended probability of malignant lesions as outlined by the O-RADS risk stratification system. When O-RADS US scores 4 and 5 were combined as a predictor for malignancy, O-RADS US showed a high sensitivity and moderate specificity. Clinical trial registration no. CRD42022352166 © RSNA, 2023 Supplemental material is available for this article. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Radiological Society of North America | - |
dc.relation.isPartOf | RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Databases, Factual | - |
dc.subject.MESH | Extremities | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neoplasms* | - |
dc.subject.MESH | Ovary* | - |
dc.title | O-RADS US: A Systematic Review and Meta-Analysis of Category-specific Malignancy Rates | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Sunyoung Lee | - |
dc.contributor.googleauthor | Ji Eun Lee | - |
dc.contributor.googleauthor | Jeong Ah Hwang | - |
dc.contributor.googleauthor | Hyejung Shin | - |
dc.identifier.doi | 10.1148/radiol.223269 | - |
dc.contributor.localId | A05659 | - |
dc.relation.journalcode | J02596 | - |
dc.identifier.eissn | 1527-1315 | - |
dc.identifier.pmid | 37642566 | - |
dc.identifier.url | https://pubs.rsna.org/doi/10.1148/radiol.223269 | - |
dc.contributor.alternativeName | Lee, Sunyoung | - |
dc.contributor.affiliatedAuthor | 이선영 | - |
dc.citation.volume | 308 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | e223269 | - |
dc.identifier.bibliographicCitation | RADIOLOGY, Vol.308(2) : e223269, 2023-08 | - |
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