Cited 30 times in
Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging of focal vertebral bone marrow lesions: initial experience of the differentiation of nodular hyperplastic hematopoietic bone marrow from malignant lesions
DC Field | Value | Language |
---|---|---|
dc.date.accessioned | 2023-08-09T02:51:59Z | - |
dc.date.available | 2023-08-09T02:51:59Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.issn | 0364-2348 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195895 | - |
dc.description.abstract | Objective: To evaluate the ability of intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) parameters to differentiate nodular hyperplastic hematopoietic bone marrow (HHBM) from malignant vertebral bone marrow lesions (VBMLs). Materials and methods: A total of 33 patients with 58 VBMLs, including 9 nodular HHBM lesions, 39 bone metastases, and 10 myelomas, were retrospectively assessed. All diagnoses were confirmed either pathologically or via image assessment. IVIM diffusion-weighted MRI with 11 b values (from 0 to 800 s/mm2) were obtained using a 3.0-T MR imager. The apparent diffusion coefficient (ADC), pure diffusion coefficient (D), perfusion fraction (f), and pseudodiffusion coefficient (D*) were calculated. ADC and IVIM parameters were compared using the Mann-Whitney U test. Receiver operating characteristic (ROC) curve analysis was performed to assess the diagnostic performances of ADC, D, f, and D* in terms of VBML characterization. The diagnostic performance of morphological MR sequences was also assessed for comparison. Results: The ADC and D values of nodular HHBM were significantly lower than those of malignant VBML (both p values < 0.001), whereas the f value was significantly higher (p < 0.001). However, there were no significant differences in D* between the two groups (p = 0.688). On ROC analysis, the area under the curve (AUC) for D was 1.000, which was significantly larger than that for ADC (AUC = 0.902). Conclusion: Intravoxel incoherent motion diffusion-weighted MRI can be used to differentiate between nodular HHBM and malignant VBML. The D value was significantly lower for nodular HHBM, and afforded a better diagnostic performance than the ADC, f, and D* values in terms of such differentiation. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer Verlag | - |
dc.relation.isPartOf | SKELETAL RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Bone Marrow / diagnostic imaging | - |
dc.subject.MESH | Bone Marrow Diseases / diagnostic imaging | - |
dc.subject.MESH | Bone Marrow Neoplasms / diagnostic imaging* | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | Diffusion Magnetic Resonance Imaging / methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Spinal Neoplasms / diagnostic imaging* | - |
dc.subject.MESH | Spine / diagnostic imaging | - |
dc.title | Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging of focal vertebral bone marrow lesions: initial experience of the differentiation of nodular hyperplastic hematopoietic bone marrow from malignant lesions | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) | - |
dc.contributor.googleauthor | Sunghoon Park | - |
dc.contributor.googleauthor | Kyu-Sung Kwack | - |
dc.contributor.googleauthor | Nam-Su Chung | - |
dc.contributor.googleauthor | Jinwoo Hwang | - |
dc.contributor.googleauthor | Hyun Young Lee | - |
dc.contributor.googleauthor | Jae Ho Kim | - |
dc.identifier.doi | 10.1007/s00256-017-2603-z | - |
dc.relation.journalcode | J02660 | - |
dc.identifier.eissn | 1432-2161 | - |
dc.identifier.pmid | 28265697 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s00256-017-2603-z | - |
dc.subject.keyword | Bone marrow | - |
dc.subject.keyword | Diffusion | - |
dc.subject.keyword | Hyperplastic hematopoietic bone marrow | - |
dc.subject.keyword | Intravoxel incoherent motion | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Metastasis | - |
dc.subject.keyword | Spine | - |
dc.citation.volume | 46 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 675 | - |
dc.citation.endPage | 683 | - |
dc.identifier.bibliographicCitation | SKELETAL RADIOLOGY, Vol.46(5) : 675-683, 2017-03 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.