Cited 5 times in
Risks of colorectal advanced neoplasia in young adults versus those of screening colonoscopy in patients aged 50 to 54 years
DC Field | Value | Language |
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dc.date.accessioned | 2023-08-09T02:42:41Z | - |
dc.date.available | 2023-08-09T02:42:41Z | - |
dc.date.issued | 2017-11 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195767 | - |
dc.description.abstract | Background and aim: The role of screening or diagnostic colonoscopy to detect advanced neoplasia in young cohorts of age < 50 is unclear. This study compared the risk of colorectal neoplasia in a young age cohort against that in 50-54s screening cohort. Methods: A multi-center retrospective study was conducted at 14 university hospitals to compare the detection rates of neoplasia and advanced neoplasia in screening or diagnostic colonoscopy in the young cohort of < 50s against those in screening colonoscopy in the 50-54s cohort. Results: Among 10 477 eligible subjects, 9765 subjects were enrolled after excluding 712 subjects. Advanced neoplasia detection rates in the young screening cohort was significantly lower than that in the 50-54s screening cohort (5.9% vs 9.3%, P < 0.001). Compared with 50-54s screening cohort, the risk of advanced neoplasia was significantly reduced by 23%, 53%, and 54% in the 45-49s, 40-44s, and 20-39s screening cohorts, respectively. The detection rates of advanced neoplasia in the young diagnostic cohort was 5.0%, which was much lower than 11.8% in 50-54s screening cohort (P < 0.001). Compared with the 50-54s screening cohort, the risk of advanced neoplasia was significantly reduced by 50%, 66%, and 71% in the 45-49s, 40-44s, and 20-39s diagnostic cohorts, respectively. Conclusions: Colonoscopy to detect advanced neoplasia in young adults aged < 50 years should be reconsidered as their risk of advanced neoplasia on screening or diagnostic colonoscopy was much lower than those of 50-54s screening cohort; however, colonoscopy screening may be justified for high-risk 45-49s cohorts. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Colonoscopy* | - |
dc.subject.MESH | Colorectal Neoplasms / diagnosis* | - |
dc.subject.MESH | Colorectal Neoplasms / pathology | - |
dc.subject.MESH | Colorectal Neoplasms / prevention & control | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mass Screening* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk | - |
dc.title | Risks of colorectal advanced neoplasia in young adults versus those of screening colonoscopy in patients aged 50 to 54 years | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Others | - |
dc.contributor.googleauthor | Kyeong Ok Kim | - |
dc.contributor.googleauthor | Hyo-Joon Yang | - |
dc.contributor.googleauthor | Jae Myung Cha | - |
dc.contributor.googleauthor | Jeong Eun Shin | - |
dc.contributor.googleauthor | Hyun Gun Kim | - |
dc.contributor.googleauthor | Young-Seok Cho | - |
dc.contributor.googleauthor | Sun-Jin Boo | - |
dc.contributor.googleauthor | Jun Lee | - |
dc.contributor.googleauthor | Yunho Jung | - |
dc.contributor.googleauthor | Hyun Jung Lee | - |
dc.contributor.googleauthor | Kyu Chan Huh | - |
dc.contributor.googleauthor | Young-Eun Joo | - |
dc.contributor.googleauthor | Jongha Park | - |
dc.contributor.googleauthor | Chang Mo Moon | - |
dc.identifier.doi | 10.1111/jgh.13798 | - |
dc.relation.journalcode | J01417 | - |
dc.identifier.eissn | 1440-1746 | - |
dc.identifier.pmid | 28370235 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/jgh.13798 | - |
dc.subject.keyword | colonoscopy | - |
dc.subject.keyword | colorectal neoplasm | - |
dc.subject.keyword | screening | - |
dc.subject.keyword | young adults | - |
dc.citation.volume | 32 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1825 | - |
dc.citation.endPage | 1831 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.32(11) : 1825-1831, 2017-11 | - |
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