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First-Pass Recanalization with EmboTrap II in Acute Ischemic Stroke (FREE-AIS): A Multicenter Prospective Study
DC Field | Value | Language |
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dc.contributor.author | 김동준 | - |
dc.contributor.author | 김병문 | - |
dc.contributor.author | 김영대 | - |
dc.contributor.author | 김준휘 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 서상현 | - |
dc.contributor.author | 허지회 | - |
dc.contributor.author | 백장현 | - |
dc.date.accessioned | 2023-03-22T02:37:36Z | - |
dc.date.available | 2023-03-22T02:37:36Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 1229-6929 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193635 | - |
dc.description.abstract | Objective: We aimed to evaluate the efficacy of EmboTrap II in terms of first-pass recanalization and to determine whether it could yield favorable outcomes. Materials and methods: In this multicenter, prospective study, we consecutively enrolled patients who underwent mechanical thrombectomy using EmboTrap II as a front-line device. The primary outcome was the first pass effect (FPE) rate defined by modified Thrombolysis In Cerebral Infarction (mTICI) grade 2c or 3 by the first pass of EmboTrap II. In addition, modified FPE (mFPE; mTICI grade 2b-3 by the first pass of EmboTrap II), successful recanalization (final mTICI grade 2b-3), and clinical outcomes were assessed. We also analyzed the effect of FPE on a modified Rankin Scale (mRS) score of 0-2 at 3 months. Results: Two hundred-ten patients (mean age ± standard deviation, 73.3 ± 11.4 years; male, 55.7%) were included. Ninety-nine patients (47.1%) had FPE, and mFPE was achieved in 150 (71.4%) patients. Successful recanalization was achieved in 191 (91.0%) patients. Among them, 164 (85.9%) patients underwent successful recanalization by exclusively using EmboTrap II. The time from groin puncture to FPE was 25.0 minutes (interquartile range, 17.0-35.0 minutes). Procedure-related complications were observed in seven (3.3%) patients. Symptomatic intracranial hemorrhage developed in 14 (6.7%) patients. One hundred twenty-three (58.9% of 209 completely followed) patients had an mRS score of 0-2. Sixteen (7.7% of 209) patients died during the follow-up period. Patients who had successful recanalization with FPE were four times more likely to have an mRS score of 0-2 than those who had successful recanalization without FPE (adjusted odds ratio, 4.13; 95% confidence interval, 1.59-10.8; p = 0.004). Conclusion: Mechanical thrombectomy using the front-line EmboTrap II is effective and safe. In particular, FPE rates were high. Achieving FPE was important for an mRS score of 0-2, even in patients with successful recanalization. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Korean Society of Radiology | - |
dc.relation.isPartOf | KOREAN JOURNAL OF RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Brain Ischemia* / diagnostic imaging | - |
dc.subject.MESH | Brain Ischemia* / surgery | - |
dc.subject.MESH | Cerebral Infarction | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ischemic Stroke* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Stents | - |
dc.subject.MESH | Stroke* / diagnostic imaging | - |
dc.subject.MESH | Stroke* / surgery | - |
dc.subject.MESH | Thrombectomy | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | First-Pass Recanalization with EmboTrap II in Acute Ischemic Stroke (FREE-AIS): A Multicenter Prospective Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Jang-Hyun Baek | - |
dc.contributor.googleauthor | Byung Moon Kim | - |
dc.contributor.googleauthor | Sang Hyun Suh | - |
dc.contributor.googleauthor | Hong-Jun Jeon | - |
dc.contributor.googleauthor | Eun Hyun Ihm | - |
dc.contributor.googleauthor | Hyungjong Park | - |
dc.contributor.googleauthor | Chang-Hyun Kim | - |
dc.contributor.googleauthor | Sang-Hoon Cha | - |
dc.contributor.googleauthor | Chi-Hoon Choi | - |
dc.contributor.googleauthor | Kyung Sik Yi | - |
dc.contributor.googleauthor | Jun-Hwee Kim | - |
dc.contributor.googleauthor | Sangil Suh | - |
dc.contributor.googleauthor | Byungjun Kim | - |
dc.contributor.googleauthor | Yoonkyung Chang | - |
dc.contributor.googleauthor | So Yeon Kim | - |
dc.contributor.googleauthor | Jae Sang Oh | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.contributor.googleauthor | Dong Joon Kim | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.identifier.doi | 10.3348/kjr.2022.0618 | - |
dc.contributor.localId | A00410 | - |
dc.contributor.localId | A00498 | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A05754 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A01886 | - |
dc.contributor.localId | A04369 | - |
dc.relation.journalcode | J02884 | - |
dc.identifier.eissn | 2005-8330 | - |
dc.identifier.pmid | 36725355 | - |
dc.subject.keyword | First-pass recanalization | - |
dc.subject.keyword | Stent | - |
dc.subject.keyword | Stroke | - |
dc.subject.keyword | Thrombectomy | - |
dc.contributor.alternativeName | Kim, Dong Joon | - |
dc.contributor.affiliatedAuthor | 김동준 | - |
dc.contributor.affiliatedAuthor | 김병문 | - |
dc.contributor.affiliatedAuthor | 김영대 | - |
dc.contributor.affiliatedAuthor | 김준휘 | - |
dc.contributor.affiliatedAuthor | 남효석 | - |
dc.contributor.affiliatedAuthor | 서상현 | - |
dc.contributor.affiliatedAuthor | 허지회 | - |
dc.citation.volume | 24 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 145 | - |
dc.citation.endPage | 154 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF RADIOLOGY, Vol.24(2) : 145-154, 2023-02 | - |
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