Cited 2 times in
Inverse Relationship between Serum 25-Hydroxyvitamin D and Elevated Intraocular Pressure
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권유진 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 정보영 | - |
dc.date.accessioned | 2023-03-22T02:17:27Z | - |
dc.date.available | 2023-03-22T02:17:27Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193560 | - |
dc.description.abstract | Elevated intraocular pressure (EIOP) is the only major modifiable risk factor of glaucoma. While low serum vitamin D levels are considered a potential risk factor for glaucoma, there is conflicting evidence on the relationship between vitamin D and EIOP despite the possible linkage between vitamin D and intraocular pressure through oxidative stress and systemic inflammation. Therefore, the aim of this study is to verify the relationship between 25-hydroxyvitamin D [25(OH)D] and EIOP using data from 15,338 individuals who visited the health promotion center of an education hospital. The cubic spline curve revealed an inverse dose-dependent association between serum 25(OH)D level and EIOP. Using multiple logistic regression analysis, the fully adjusted odds ratio (OR) with 95% confidence interval (CI) for the EIOP of the serum 25(OH)D per increment was 0.97 (0.96-0.990). The fully adjusted ORs (95% CIs) for the EIOP of the 25(OH)D insufficiency and 25(OH)D sufficiency groups, compared to 25(OH)D deficiency group, were 0.72 (0.56-0.92) and 0.51 (0.34-0.78), respectively. The relationship remained significant in male and young age subgroups. In conclusion, the clinical assessment of intraocular pressure may prove helpful when treating patients with 25(OH)D deficiency, which may be a preventive strategy against the development of glaucoma. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI Publishing | - |
dc.relation.isPartOf | NUTRIENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Calcifediol | - |
dc.subject.MESH | Glaucoma* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Vitamin D | - |
dc.subject.MESH | Vitamin D Deficiency* / epidemiology | - |
dc.title | Inverse Relationship between Serum 25-Hydroxyvitamin D and Elevated Intraocular Pressure | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Jun-Hyuk Lee | - |
dc.contributor.googleauthor | Yu-Jin Kwon | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Jee Hye Han | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.contributor.googleauthor | Sung Jin Kim | - |
dc.identifier.doi | 10.3390/nu15020423 | - |
dc.contributor.localId | A04882 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A03609 | - |
dc.relation.journalcode | J02396 | - |
dc.identifier.eissn | 2072-6643 | - |
dc.identifier.pmid | 36678294 | - |
dc.subject.keyword | 25-hydroxyvitamin D | - |
dc.subject.keyword | glaucoma | - |
dc.subject.keyword | intraocular pressure | - |
dc.contributor.alternativeName | Kwon, Yu-Jin | - |
dc.contributor.affiliatedAuthor | 권유진 | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.contributor.affiliatedAuthor | 정보영 | - |
dc.citation.volume | 15 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 423 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, Vol.15(2) : 423, 2023-01 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.