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Clinical features and long-term treatment outcome of posterior scleritis

Authors
 Dong Hyun Lee  ;  Hyuna Cho  ;  Eun Young Choi  ;  Min Kim 
Citation
 ANNALS OF TRANSLATIONAL MEDICINE, Vol.10(21) : 1162, 2022-11 
Journal Title
ANNALS OF TRANSLATIONAL MEDICINE
ISSN
 2305-5847 
Issue Date
2022-11
Keywords
Posterior scleritis ; infectious scleritis ; uveitis
Abstract
Background: To analyze the clinical characteristics and long-term treatment outcomes of patients with posterior scleritis.

Methods: This retrospective, observational case series analyzed medical records of 14 patients diagnosed with infectious or non-infectious posterior scleritis between May 2005 and March 2020 at Severance Hospital and Gangnam Severance Hospital.

Results: A total of 12 patients with non-infectious and two with infectious posterior scleritis were treated. Conjunctival injection (85.7%) was the most common symptom, followed by pain on eyeball movement (57.1%), and decreased visual acuity (42.9%). Anterior uveitis (64.3%) was the most common associated clinical finding. In five eyes (35.7%), immunosuppressive agents were administered in addition to corticosteroids to control the inflammation. Recurrence was noted in three eyes (21.4%), all of them showing non-infectious scleritis. The final visual acuity of the patients did not show significant change compared to that at the first visit (P=0.878).

Conclusions: Most posterior scleritis patients were of non-infectious type and some needed additional immunosuppressive treatment. In patients with a history of ocular surgery or trauma, especially with the presence of pus-containing nodules, infectious posterior scleritis should always be considered. Since impaired vision does not improve significantly after treatment of posterior scleritis, prompt diagnosis and aggressive treatment are recommended.
Files in This Item:
T202205867.pdf Download
DOI
10.21037/atm-22-721
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min(김민) ORCID logo https://orcid.org/0000-0003-1873-6959
Lee, Dong Hyun(이동현)
Choi, Eun Young(최은영) ORCID logo https://orcid.org/0000-0002-1668-6452
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/192825
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