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Coexistence of condyloma acuminatum and extramammary Paget's disease on penis and scrotum: A rare case report

Authors
 Inho Kang  ;  Joon Ho Lee  ;  Jong Im Lee  ;  Joon Shik Hong  ;  Young Woong Mo  ;  Gyu Yong Jung 
Citation
 MEDICINE, Vol.101(45) : e31754, 2022-11 
Journal Title
MEDICINE
ISSN
 0025-7974 
Issue Date
2022-11
MeSH
Aged ; Condylomata Acuminata* / complications ; Condylomata Acuminata* / diagnosis ; Condylomata Acuminata* / surgery ; Female ; Humans ; Male ; Paget Disease, Extramammary* / diagnosis ; Paget Disease, Extramammary* / surgery ; Penis / pathology ; Scrotum / pathology ; Skin Neoplasms* / pathology
Abstract
Rationale: Extramammary Paget's disease (EMPD) is a rare skin cancer that commonly occurs in sites rich in apocrine glands, such as perineum, vulva, axilla, scrotum, and penis. On the other hand, condyloma acuminatum (CA; also referred to as anogenital warts) is a common benign neoplasm caused by human papillomavirus. Few cases of coexistent EMPD and CA have been reported because of the rarity of the condition.

Patient concerns and diagnosis: A 72-year-old man with a genital mass, which appeared to be composed of multiple papillomatous masses, was referred for surgical resection. The lesion was first noticed 6 months previously and grew rapidly. CO2 ablative laser therapy was performed twice at a primary clinic, but the mass recurred.

Intervention and outcomes: Excisional biopsy revealed the presence of coexistent EMPD and CA. Additional wide excision was performed, and postoperative biopsy confirmed no residual tumor. Two years after surgery, no recurrence had occurred.

Lessons: CA can co-occur with several types of skin malignancies, and a skin malignancy coexisting with CA is difficult to diagnose visually. Therefore, even if a skin lesion in the genital region is considered to be CA, we recommend punch biopsy before treatment because it can benefit prognosiss.
Files in This Item:
T9992022506.pdf Download
DOI
10.1097/MD.0000000000031754
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
Yonsei Authors
Mo, Young Woong(모영웅) ORCID logo https://orcid.org/0000-0002-4180-3139
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/192330
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