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Isolated Diastolic Hypertension and Risk of Cardiovascular Disease: Controversies in Hypertension - Pro Side of the Argument

Authors
 Yuichiro Yano  ;  Hyeon Chang Kim  ;  Hokyou Lee  ;  Nazar Azahar  ;  Sabrina Ahmed  ;  Kaori Kitaoka  ;  Hidehiro Kaneko  ;  Fujimi Kawai  ;  Atsushi Mizuno  ;  Anthony J Viera 
Citation
 HYPERTENSION, Vol.79(8) : 1563-1570, 2022-08 
Journal Title
HYPERTENSION
ISSN
 0194-911X 
Issue Date
2022-08
MeSH
Adult ; Blood Pressure ; Cardiovascular Diseases* / complications ; Cardiovascular Diseases* / etiology ; Humans ; Hypertension* / complications ; Hypertension* / drug therapy ; Hypertension* / epidemiology ; Risk Factors ; Systole
Keywords
association ; awareness ; blood pressure ; cardiovascular diseases ; risk factors
Abstract
Isolated diastolic hypertension (IDH), defined as diastolic blood pressure in the hypertensive range but systolic blood pressure not in the hypertensive range, is not uncommon (<20%) among adults with hypertension. IDH often manifests in concurrence with other cardiovascular risk factors. Individuals with IDH tend to have lower awareness of their hypertension compared with those with both systolic and diastolic hypertension. IDH appears to be a largely underrated risk factor for cardiovascular disease events, which may be explained by inconsistent association of IDH with cardiovascular disease events. The inconsistency suggests that IDH is heterogeneous. One size does not seem to fit all in the clinical management of individuals with IDH. Rather than treating IDH as a monolithic low-risk condition, detailed phenotyping in the context of individual comprehensive cardiovascular risk would seem to be most useful to assess an individual's expected net benefit from therapy. In this review, we highlight that the clinical relevance of IDH differs by individual clinical characteristics, and elucidate groups of individuals with IDH that should be wary of cardiovascular disease risks.
Full Text
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.122.18459?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
DOI
10.1161/HYPERTENSIONAHA.122.18459
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyeon Chang(김현창) ORCID logo https://orcid.org/0000-0001-7867-1240
Lee, Hokyou(이호규) ORCID logo https://orcid.org/0000-0002-5034-8422
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191829
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