Cited 1 times in
Laboratory information management system for COVID-19 non-clinical efficacy trial data
DC Field | Value | Language |
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dc.contributor.author | 김성희 | - |
dc.contributor.author | 박인호 | - |
dc.contributor.author | 서준영 | - |
dc.contributor.author | 남기택 | - |
dc.contributor.author | 신전수 | - |
dc.date.accessioned | 2022-12-22T02:12:49Z | - |
dc.date.available | 2022-12-22T02:12:49Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 1738-6055 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/191495 | - |
dc.description.abstract | Background: As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus disease 2019 (COVID-19) pandemic, a number of global efforts are underway to develop vaccines and therapeutics. We are therefore observing an explosion in the proliferation of COVID-19 data, and interoperability is highly requested in multiple institutions participating simultaneously in COVID-19 pandemic research. Results: In this study, a laboratory information management system (LIMS) approach has been adopted to systemically manage various COVID-19 non-clinical trial data, including mortality, clinical signs, body weight, body temperature, organ weights, viral titer (viral replication and viral RNA), and multiorgan histopathology, from multiple institutions based on a web interface. The main aim of the implemented system is to integrate, standardize, and organize data collected from laboratories in multiple institutes for COVID-19 non-clinical efficacy testings. Six animal biosafety level 3 institutions proved the feasibility of our system. Substantial benefits were shown by maximizing collaborative high-quality non-clinical research. Conclusions: This LIMS platform can be used for future outbreaks, leading to accelerated medical product development through the systematic management of extensive data from non-clinical animal studies. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 한국실험동물학회 | - |
dc.relation.isPartOf | Laboratory Animal Research | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Laboratory information management system for COVID-19 non-clinical efficacy trial data | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | BioMedical Science Institute (의생명과학부) | - |
dc.contributor.googleauthor | Suhyeon Yoon | - |
dc.contributor.googleauthor | Hyuna Noh | - |
dc.contributor.googleauthor | Heejin Jin | - |
dc.contributor.googleauthor | Sungyoung Lee | - |
dc.contributor.googleauthor | Soyul Han | - |
dc.contributor.googleauthor | Sung-Hee Kim | - |
dc.contributor.googleauthor | Jiseon Kim | - |
dc.contributor.googleauthor | Jung Seon Seo | - |
dc.contributor.googleauthor | Jeong Jin Kim | - |
dc.contributor.googleauthor | In Ho Park | - |
dc.contributor.googleauthor | Jooyeon Oh | - |
dc.contributor.googleauthor | Joon-Yong Bae | - |
dc.contributor.googleauthor | Gee Eun Lee | - |
dc.contributor.googleauthor | Sun-Je Woo | - |
dc.contributor.googleauthor | Sun-Min Seo | - |
dc.contributor.googleauthor | Na-Won Kim | - |
dc.contributor.googleauthor | Youn Woo Lee | - |
dc.contributor.googleauthor | Hui Jeong Jang | - |
dc.contributor.googleauthor | Seung-Min Hong | - |
dc.contributor.googleauthor | Se-Hee An | - |
dc.contributor.googleauthor | Kwang-Soo Lyoo | - |
dc.contributor.googleauthor | Minjoo Yeom | - |
dc.contributor.googleauthor | Hanbyeul Lee | - |
dc.contributor.googleauthor | Bud Jung | - |
dc.contributor.googleauthor | Sun-Woo Yoon | - |
dc.contributor.googleauthor | Jung-Ah Kang | - |
dc.contributor.googleauthor | Sang-Hyuk Seok | - |
dc.contributor.googleauthor | Yu Jin Lee | - |
dc.contributor.googleauthor | Seo Yeon Kim | - |
dc.contributor.googleauthor | Young Been Kim | - |
dc.contributor.googleauthor | Ji-Yeon Hwang | - |
dc.contributor.googleauthor | Dain On | - |
dc.contributor.googleauthor | Soo-Yeon Lim | - |
dc.contributor.googleauthor | Sol Pin Kim | - |
dc.contributor.googleauthor | Ji Yun Jang | - |
dc.contributor.googleauthor | Ho Lee | - |
dc.contributor.googleauthor | Kyoungmi Kim | - |
dc.contributor.googleauthor | Hyo-Jung Lee | - |
dc.contributor.googleauthor | Hong Bin Kim | - |
dc.contributor.googleauthor | Jun Won Park | - |
dc.contributor.googleauthor | Dae Gwin Jeong | - |
dc.contributor.googleauthor | Daesub Song | - |
dc.contributor.googleauthor | Kang-Seuk Choi | - |
dc.contributor.googleauthor | Ho-Young Lee | - |
dc.contributor.googleauthor | Yang-Kyu Choi | - |
dc.contributor.googleauthor | Jung-Ah Choi | - |
dc.contributor.googleauthor | Manki Song | - |
dc.contributor.googleauthor | Man-Seong Park | - |
dc.contributor.googleauthor | Jun-Young Seo | - |
dc.contributor.googleauthor | Ki Taek Nam | - |
dc.contributor.googleauthor | Jeon-Soo Shin | - |
dc.contributor.googleauthor | Sungho Won | - |
dc.contributor.googleauthor | Jun-Won Yun | - |
dc.contributor.googleauthor | Je Kyung Seong | - |
dc.identifier.doi | 10.1186/s42826-022-00127-2 | - |
dc.contributor.localId | A06017 | - |
dc.contributor.localId | A01631 | - |
dc.contributor.localId | A01911 | - |
dc.contributor.localId | A01243 | - |
dc.contributor.localId | A02144 | - |
dc.relation.journalcode | J02149 | - |
dc.identifier.eissn | 2233-7660 | - |
dc.identifier.pmid | 35765097 | - |
dc.subject.keyword | COVID-19 | - |
dc.subject.keyword | Data | - |
dc.subject.keyword | Laboratory information management system | - |
dc.subject.keyword | Non-clinical | - |
dc.subject.keyword | SARS-CoV-2 | - |
dc.contributor.alternativeName | Kim, Sung-Hee | - |
dc.contributor.affiliatedAuthor | 김성희 | - |
dc.contributor.affiliatedAuthor | 박인호 | - |
dc.contributor.affiliatedAuthor | 서준영 | - |
dc.contributor.affiliatedAuthor | 남기택 | - |
dc.contributor.affiliatedAuthor | 신전수 | - |
dc.citation.volume | 38 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 17 | - |
dc.identifier.bibliographicCitation | Laboratory Animal Research, Vol.38(1) : 17, 2022-06 | - |
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