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Feasibility of Ultrasound Attenuation Imaging for Assessing Pediatric Hepatic Steatosis

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dc.contributor.author송경철-
dc.contributor.author신현주-
dc.contributor.author장동률-
dc.contributor.author채현욱-
dc.date.accessioned2022-08-23T00:40:28Z-
dc.date.available2022-08-23T00:40:28Z-
dc.date.issued2022-07-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/189559-
dc.description.abstractWe investigated the feasibility of ultrasound attenuation imaging (ATI) for assessing pediatric hepatic steatosis. A total of 111 children and adolescents who underwent liver ultrasonography with ATI for suspected hepatic steatosis were included. Participants were classified into the normal, mild, or moderate–severe fatty liver group according to grayscale US findings. Associations between clinical factors, magnetic resonance imaging proton density fat fraction, steatosis stage and ATI values were evaluated. To determine the cutoff values of ATI for staging hepatic steatosis, areas under the curve (AUCs) were analyzed. Factors that could cause measurement failure with ATI were assessed. Of 111 participants, 88 had successful measurement results. Median ATI values were significantly increased according to steatosis stage (p < 0.001). Body mass index (BMI) was a significant factor for increased ATI values (p = 0.047). To differentiate fatty liver from normal liver, a cutoff value of 0.59 dB/cm/MHz could be used with an AUC value of 0.853. To differentiate moderate to severe fatty liver from mild fatty liver, a cutoff value of 0.69 dB/cm/MHz could be used with an AUC value up to 0.91. ATI can be used in children as an effective ultrasonography technique for quantifying and staging pediatric hepatic steatosis.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI-
dc.relation.isPartOfBIOLOGY-BASEL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleFeasibility of Ultrasound Attenuation Imaging for Assessing Pediatric Hepatic Steatosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학교실)-
dc.contributor.googleauthorKyungchul Song-
dc.contributor.googleauthorNak-Hoon Son-
dc.contributor.googleauthorDong Ryul Chang-
dc.contributor.googleauthorHyun Wook Chae-
dc.contributor.googleauthorHyun Joo Shin-
dc.identifier.doi10.3390/biology11071087-
dc.contributor.localIdA06013-
dc.contributor.localIdA02178-
dc.contributor.localIdA05938-
dc.contributor.localIdA04026-
dc.relation.journalcodeJ03994-
dc.identifier.eissn2079-7737-
dc.subject.keywordultrasonography-
dc.subject.keywordliver steatosis-
dc.subject.keywordattenuation imaging-
dc.subject.keywordfat quantification-
dc.subject.keywordchildren-
dc.contributor.alternativeNameSong, Kyungchul-
dc.contributor.affiliatedAuthor송경철-
dc.contributor.affiliatedAuthor신현주-
dc.contributor.affiliatedAuthor장동률-
dc.contributor.affiliatedAuthor채현욱-
dc.citation.volume11-
dc.citation.number7-
dc.citation.startPage1087-
dc.identifier.bibliographicCitationBIOLOGY-BASEL, Vol.11(7) : 1087, 2022-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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