0 63

Cited 0 times in

Predictors of Sarcopenia in an Obese Asian Population

Authors
 Min Je Sung  ;  Jun Yong Park  ;  Hye Won Lee  ;  Beom Kyung Kim  ;  Do Young Kim  ;  Sang Hoon Ahn  ;  Seung Up Kim 
Citation
 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, Vol.74(2) : 505-514, 2022-02 
Journal Title
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
ISSN
 0163-5581 
Issue Date
2022-02
MeSH
Aged ; Asians ; Body Mass Index ; Female ; Humans ; Male ; Middle Aged ; Muscle, Skeletal / physiopathology* ; Non-alcoholic Fatty Liver Disease* ; Obesity* / complications ; Obesity* / epidemiology ; Risk Factors ; Sarcopenia* / epidemiology ; Sarcopenia* / etiology
Abstract
Sarcopenia is associated with obesity and might also be responsible for other disorders. Here, we investigated the prevalence of sarcopenia and its predictors in obese subjects. Subjects who underwent a medical health checkup and living-related liver donors were recruited. Obesity was defined as body mass index (BMI) ≥25 kg/m2. Muscle mass was assessed using computed tomography at the 3rd lumbar vertebra. The lowest quartile of the lumbar skeletal muscle index (LSMI) was considered sarcopenia. Among 466 obese subjects, 53 (11.4%) had sarcopenia. Subjects with sarcopenia were significantly older (mean 66.6 vs. 53.3 years) and had a significantly higher prevalence of hypertension (62.3 vs. 46.0%) and diabetes (45.3 vs. 31.0%), higher fibrosis-4 (FIB-4) index (mean 1.57 vs. 1.16), and higher atherosclerotic cardiovascular disease (ASCVD) risk score (mean 22.86% vs. 11.15%), whereas they had a significantly lower prevalence of female gender (13.2% vs. 27.8%), lower BMI (mean 26.4 vs. 27.4 kg/m2), and lower LSMI (mean 43 vs. 56 cm2/m2) than subjects without sarcopenia (all P < 0.05). On multivariate analysis, higher BMI (odd ratio [OR] = 0.599, P = 0.001) was independently associated with a reduced risk of sarcopenia, whereas higher ASCVD risk scores (OR = 1.045, P < 0.001) were independently associated with an increased risk of sarcopenia. Sarcopenia is significantly associated with lower BMI and higher cardiovascular risk in an obese Asian population.
Full Text
https://www.tandfonline.com/doi/full/10.1080/01635581.2021.1895232
DOI
10.1080/01635581.2021.1895232
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영)
Kim, Beom Kyung(김범경) ORCID logo https://orcid.org/0000-0002-5363-2496
Kim, Seung Up(김승업) ORCID logo https://orcid.org/0000-0002-9658-8050
Park, Jun Yong(박준용) ORCID logo https://orcid.org/0000-0001-6324-2224
Sung, Min Je(성민제) ORCID logo https://orcid.org/0000-0001-5395-8851
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
Lee, Hye Won(이혜원) ORCID logo https://orcid.org/0000-0002-3552-3560
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/189296
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links