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Predictors of Sarcopenia in an Obese Asian Population

DC Field Value Language
dc.contributor.author김도영-
dc.contributor.author김범경-
dc.contributor.author김승업-
dc.contributor.author박준용-
dc.contributor.author성민제-
dc.contributor.author안상훈-
dc.contributor.author이혜원-
dc.date.accessioned2022-08-23T00:10:33Z-
dc.date.available2022-08-23T00:10:33Z-
dc.date.issued2022-02-
dc.identifier.issn0163-5581-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/189296-
dc.description.abstractSarcopenia is associated with obesity and might also be responsible for other disorders. Here, we investigated the prevalence of sarcopenia and its predictors in obese subjects. Subjects who underwent a medical health checkup and living-related liver donors were recruited. Obesity was defined as body mass index (BMI) ≥25 kg/m2. Muscle mass was assessed using computed tomography at the 3rd lumbar vertebra. The lowest quartile of the lumbar skeletal muscle index (LSMI) was considered sarcopenia. Among 466 obese subjects, 53 (11.4%) had sarcopenia. Subjects with sarcopenia were significantly older (mean 66.6 vs. 53.3 years) and had a significantly higher prevalence of hypertension (62.3 vs. 46.0%) and diabetes (45.3 vs. 31.0%), higher fibrosis-4 (FIB-4) index (mean 1.57 vs. 1.16), and higher atherosclerotic cardiovascular disease (ASCVD) risk score (mean 22.86% vs. 11.15%), whereas they had a significantly lower prevalence of female gender (13.2% vs. 27.8%), lower BMI (mean 26.4 vs. 27.4 kg/m2), and lower LSMI (mean 43 vs. 56 cm2/m2) than subjects without sarcopenia (all P < 0.05). On multivariate analysis, higher BMI (odd ratio [OR] = 0.599, P = 0.001) was independently associated with a reduced risk of sarcopenia, whereas higher ASCVD risk scores (OR = 1.045, P < 0.001) were independently associated with an increased risk of sarcopenia. Sarcopenia is significantly associated with lower BMI and higher cardiovascular risk in an obese Asian population.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherRoutledge-
dc.relation.isPartOfNUTRITION AND CANCER-AN INTERNATIONAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHAsians-
dc.subject.MESHBody Mass Index-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMuscle, Skeletal / physiopathology*-
dc.subject.MESHNon-alcoholic Fatty Liver Disease*-
dc.subject.MESHObesity* / complications-
dc.subject.MESHObesity* / epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHSarcopenia* / epidemiology-
dc.subject.MESHSarcopenia* / etiology-
dc.titlePredictors of Sarcopenia in an Obese Asian Population-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorMin Je Sung-
dc.contributor.googleauthorJun Yong Park-
dc.contributor.googleauthorHye Won Lee-
dc.contributor.googleauthorBeom Kyung Kim-
dc.contributor.googleauthorDo Young Kim-
dc.contributor.googleauthorSang Hoon Ahn-
dc.contributor.googleauthorSeung Up Kim-
dc.identifier.doi10.1080/01635581.2021.1895232-
dc.contributor.localIdA00385-
dc.contributor.localIdA00487-
dc.contributor.localIdA00654-
dc.contributor.localIdA01675-
dc.contributor.localIdA05975-
dc.contributor.localIdA02226-
dc.contributor.localIdA03318-
dc.relation.journalcodeJ02399-
dc.identifier.eissn1532-7914-
dc.identifier.pmid33733940-
dc.identifier.urlhttps://www.tandfonline.com/doi/full/10.1080/01635581.2021.1895232-
dc.contributor.alternativeNameKim, Do Young-
dc.contributor.affiliatedAuthor김도영-
dc.contributor.affiliatedAuthor김범경-
dc.contributor.affiliatedAuthor김승업-
dc.contributor.affiliatedAuthor박준용-
dc.contributor.affiliatedAuthor성민제-
dc.contributor.affiliatedAuthor안상훈-
dc.contributor.affiliatedAuthor이혜원-
dc.citation.volume74-
dc.citation.number2-
dc.citation.startPage505-
dc.citation.endPage514-
dc.identifier.bibliographicCitationNUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, Vol.74(2) : 505-514, 2022-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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