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Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy

 Seung Yong Shin  ;  Kyeong Seon Ga  ;  In Young Kim  ;  Yoo Mi Park  ;  Da Hyun Jung  ;  Jie-Hyun Kim  ;  Young Hoon Youn  ;  Hyojin Park  ;  Jae Jun Park 
 SCIENTIFIC REPORTS, Vol.9(1) : 19715, 2019-12 
Journal Title
Issue Date
Ascorbic Acid / pharmacology* ; Cathartics / pharmacology* ; Colonoscopy* ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Outpatients* ; Polyethylene Glycols / pharmacology* ; Risk Factors
Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are widely used for bowel cleansing before colonoscopy. This study aimed to investigate the pre-endoscopic predictive factors for inadequate preparation in subjects receiving low-volume PEG plus ascorbic acid. A prospective study was performed at Gangnam Severance Hospital, Korea, from June 2016 to December 2016. All participants received low-volume PEG plus ascorbic acid solutions for outpatient colonoscopy. The split-dose bowel preparation was administered in subject with morning colonoscopy while same day bowel preparation was used for afternoon colonoscopy. 715 patients were enrolled (mean age 56.1 years, 54.4% male), of which 138 (19.3%) had an inadequate bowel preparation. In multivariable analysis, cirrhosis (OR 4.943, 95% CI 1.191-20.515), low (less than 70%) compliance for three-day low-residual diet (OR 2.165, 95% CI 1.333-3.515), brown liquid rectal effluent (compared with clear or semi-clear effluent) (OR 7.604, 95% CI, 1.760-32.857), and longer time interval (>= 2 hours) between last defecation and colonoscopic examination (OR 1.841, 95% CI, 1.190-2.849) were found as an independent predictors for inadequate preparation. These predictive factors may be useful in guiding additional intervention to improve quality of bowel preparation.
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6. Others (기타) > Gangnam Severance Hospital Health Promotion Center(강남세브란스병원 체크업) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jie-Hyun(김지현) ORCID logo https://orcid.org/0000-0002-9198-3326
Park, Yoo Mi(박유미) ORCID logo https://orcid.org/0000-0002-3642-7300
Park, Jae Jun(박재준)
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Youn, Young Hoon(윤영훈) ORCID logo https://orcid.org/0000-0002-0071-229X
Jung, Da Hyun(정다현) ORCID logo https://orcid.org/0000-0001-6668-3113
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