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Gadoxetic acid-enhanced magnetic resonance imaging: Hepatocellular carcinoma and mimickers

DC Field Value Language
dc.contributor.author김명진-
dc.contributor.author김연윤-
dc.contributor.author박미숙-
dc.contributor.author최진영-
dc.date.accessioned2022-08-19T06:23:48Z-
dc.date.available2022-08-19T06:23:48Z-
dc.date.issued2019-09-
dc.identifier.issn2287-2728-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/189131-
dc.description.abstractGadoxetic acid, a hepatocyte-specific magnetic resonance imaging (MRI) contrast agent, has emerged as an important tool for hepatocellular carcinoma (HCC) diagnosis. Gadoxetic acid-enhanced MRI is useful for the evaluation of early-stage HCC, diagnosis of HCC precursor lesions, and highly sensitive diagnosis of HCC. Furthermore, functional information provided by gadoxetic acid-enhanced MRI can aid in the characterization of focal liver lesions. For example, whereas lesions lack functioning hepatocytes appear hypointense in the hepatobiliary phase, preserved or enhanced expression of organic anion transporting polypeptides in some HCCs as well as focal nodular hyperplasia lead to hyperintensity in the hepatobiliary phase; and a targetoid appearance on transitional phase or hepatobiliary phase imaging can be helpful for identifying the histopathological composition of tumors. While gadoxetic acid-enhanced MRI may improve the sensitivity of HCC diagnosis and provide new insights into the characterization of focal liver lesions, there are many challenges associated with its use. This article reviews the pros and cons of HCC diagnosis with gadoxetic acidenhanced MRI and discuss some clues in the radiological differentiation of HCC from HCC mimickers.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Association for the Study of the Liver-
dc.relation.isPartOfCLINICAL AND MOLECULAR HEPATOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAngiomyolipoma / diagnostic imaging-
dc.subject.MESHCarcinoma, Hepatocellular / diagnosis-
dc.subject.MESHCarcinoma, Hepatocellular / diagnostic imaging*-
dc.subject.MESHContrast Media / chemistry*-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHGadolinium DTPA / chemistry*-
dc.subject.MESHHumans-
dc.subject.MESHLiver Neoplasms / diagnosis-
dc.subject.MESHLiver Neoplasms / diagnostic imaging*-
dc.subject.MESHMagnetic Resonance Imaging*-
dc.subject.MESHbeta Catenin / genetics-
dc.titleGadoxetic acid-enhanced magnetic resonance imaging: Hepatocellular carcinoma and mimickers-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorYeun-Yoon Kim-
dc.contributor.googleauthorMi-Suk Park-
dc.contributor.googleauthorKhalid Suliman Aljoqiman-
dc.contributor.googleauthorJin-Young Choi-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.identifier.doi10.3350/cmh.2018.0107-
dc.contributor.localIdA00426-
dc.contributor.localIdA04902-
dc.contributor.localIdA01463-
dc.contributor.localIdA04200-
dc.relation.journalcodeJ00557-
dc.identifier.eissn2287-285X-
dc.identifier.pmid30661336-
dc.subject.keywordDiagnosis-
dc.subject.keywordLiver neoplasm-
dc.subject.keywordHepatocellular carcinoma-
dc.subject.keywordMagnetic resonance imaging-
dc.subject.keywordGadoxetic acid-
dc.contributor.alternativeNameKim, Myeong Jin-
dc.contributor.affiliatedAuthor김명진-
dc.contributor.affiliatedAuthor김연윤-
dc.contributor.affiliatedAuthor박미숙-
dc.contributor.affiliatedAuthor최진영-
dc.citation.volume25-
dc.citation.number3-
dc.citation.startPage223-
dc.citation.endPage233-
dc.identifier.bibliographicCitationCLINICAL AND MOLECULAR HEPATOLOGY, Vol.25(3) : 223-233, 2019-09-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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