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Real-Time Ultrasound Detection of Breast Microcalcifications Using Multifocus Twinkling Artifact Imaging

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dc.contributor.author김민정-
dc.contributor.author장원석-
dc.date.accessioned2022-07-08T03:01:18Z-
dc.date.available2022-07-08T03:01:18Z-
dc.date.issued2022-05-
dc.identifier.issn0278-0062-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/188626-
dc.description.abstractDetecting microcalcifications (MCs) in real time is important in the guidance of many breast biopsies. Due to its capability in visualizing biopsy needles without radiation hazards, ultrasound imaging is preferred over X-ray mammography, but it suffers from low sensitivity in detecting MCs. Here, we present a new nonionizing method based on real-time multifocus twinkling artifact (MF-TA) imaging for reliably detecting MCs. Our approach exploits time-varying TAs arising from acoustic random scattering on MCs with rough or irregular surfaces. To obtain the increased intensity of the TAs from MCs, in MF-TA, acoustic transmit parameters, such as the transmit frequency, the number of focuses and f-number, were optimized by investigating acoustical characteristics of MCs. A real-time MF-TA imaging sequence was developed and implemented on a programmable ultrasound research system, and it was controlled with a graphical user interface during real-time scanning. From an in-house 3D phantom and ex vivo breast specimen studies, the MF-TA method showed outstanding visibility and high-sensitivity detection for MCs regardless of their distribution or the background tissue. These results demonstrated that this nonionizing, noninvasive imaging technique has the potential to be one of effective image-guidance methods for breast biopsy procedures.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherInstitute of Electrical and Electronics Engineers-
dc.relation.isPartOfIEEE TRANSACTIONS ON MEDICAL IMAGING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHArtifacts-
dc.subject.MESHBreast Diseases*-
dc.subject.MESHCalcinosis* / diagnostic imaging-
dc.subject.MESHHumans-
dc.subject.MESHMammography / methods-
dc.subject.MESHUltrasonography-
dc.titleReal-Time Ultrasound Detection of Breast Microcalcifications Using Multifocus Twinkling Artifact Imaging-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorJinbum Kang-
dc.contributor.googleauthorKanghee Han-
dc.contributor.googleauthorIlseob Song-
dc.contributor.googleauthorKang-Sik Kim-
dc.contributor.googleauthorWon Seuk Jang-
dc.contributor.googleauthorMin Jung Kim-
dc.contributor.googleauthorYangmo Yoo-
dc.identifier.doi10.1109/TMI.2021.3136901-
dc.contributor.localIdA00473-
dc.contributor.localIdA04793-
dc.relation.journalcodeJ01028-
dc.identifier.pmid34928792-
dc.identifier.urlhttps://ieeexplore.ieee.org/document/9656728-
dc.contributor.alternativeNameKim, Min Jung-
dc.contributor.affiliatedAuthor김민정-
dc.contributor.affiliatedAuthor장원석-
dc.citation.volume41-
dc.citation.number5-
dc.citation.startPage1300-
dc.citation.endPage1308-
dc.identifier.bibliographicCitationIEEE TRANSACTIONS ON MEDICAL IMAGING, Vol.41(5) : 1300-1308, 2022-05-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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