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1. College of Medicine (의과대학)
Yonsei Advanced Medical Science Research and Education (첨단의과학교육연구단)
1. Journal Papers
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2026
An ESAT-6-convergent prime-boost vaccination combining recombinant BCG expressing Mycobacterium marinum ESX-1 and ESAT-6/GLA-SE improves TB protection
NPJ VACCINES
2026
Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies
JOURNAL OF ADVANCED RESEARCH
2026
Exploring Host-driven Immunopathological Factors Developing Severe Tuberculosis: Insights from Comparative Mouse Models
International Journal of Biological Sciences
2025
Adjunctive beneficial effect of c-di-GMP, a STING agonist, in enhancing protective efficacy of TLR4-adjuvanted tuberculosis subunit vaccine formulations
JOURNAL OF BIOMEDICAL SCIENCE
2024
Permissive lung neutrophils facilitate tuberculosis immunopathogenesis in male phagocyte NADPH oxidase-deficient mice
PLOS PATHOGENS
2024
BCG-booster vaccination with HSP90-ESAT-6-HspX-RipA multivalent subunit vaccine confers durable protection against hypervirulent Mtb in mice
NPJ VACCINES
2024
Immunogenicity and protective efficacy of RipA, a peptidoglycan hydrolase, against<i> Mycobacterium</i><i> tuberculosis</i> Beijing outbreak strains
VACCINE
2024
Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis
EXPERIMENTAL AND MOLECULAR MEDICINE
2023
Importance of adjuvant selection in tuberculosis vaccine development: Exploring basic mechanisms and clinical implications
VACCINE: X
2023
Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s
NATURE METHODS
2024
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Nature Biotechnology
2023
Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection
Immune Network
2023
Hedgehog signaling regulates Wolffian duct development through the primary cilium(dagger)
Biology of Reproduction
2022
Tissue-specific requirement of sodium channel and clathrin linker 1 (Sclt1) for ciliogenesis during limb development
Frontiers in Cell and Developmental Biology
2022
Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective as an adjunct to antibiotic treatment in chronic disease
Virulence
2022
BCG Delta BCG1419c increased memory CD8(+) T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis
SCIENTIFIC REPORTS
2022
Novel Antibacterial Activity of Febuxostat, an FDA-Approved Antigout Drug against Mycobacterium tuberculosis Infection
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2020
Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis
Vaccine
2022
Host-directed anti-mycobacterial activity of colchicine, an anti-gout drug, via strengthened host innate resistance reinforced by the IL-1 beta/PGE(2) axis
British Journal of Pharmacology
2022
Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx
Nature Communications
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