13 25

Cited 0 times in

Role of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention in Optimizing Outcomes in Acute Myocardial Infarction

Authors
 Yongcheol Kim  ;  SungA Bae  ;  Thomas W Johnson  ;  Nak-Hoon Son  ;  Doo Sun Sim  ;  Young Joon Hong  ;  Sang Wook Kim  ;  Deok-Kyu Cho  ;  Jung-Sun Kim  ;  Byeong-Keuk Kim  ;  Donghoon Choi  ;  Myeong-Ki Hong  ;  Yangsoo Jang  ;  Myung Ho Jeong 
Citation
 JOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol.11(5) : e023481, 2022-03 
Journal Title
JOURNAL OF THE AMERICAN HEART ASSOCIATION
Issue Date
2022-03
MeSH
Coronary Angiography / methods ; Coronary Artery Disease* ; Death ; Drug-Eluting Stents* ; Humans ; Myocardial Infarction* / diagnostic imaging ; Myocardial Infarction* / surgery ; Percutaneous Coronary Intervention* / adverse effects ; Percutaneous Coronary Intervention* / methods ; Treatment Outcome ; Ultrasonography, Interventional / methods
Keywords
acute myocardial infarction ; drug‐eluting stent ; intravascular ultrasound ; percutaneous coronary intervention
Abstract
Background The role of intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) is still unclear in patients with acute myocardial infarction acute myocardial infarction. This study aimed to evaluate the long-term impact of IVUS-guided PCI in patients with acute myocardial infarction. Methods and Results Among a total of 13 104 patients with acute myocardial infarction, enrolled in the Korea Acute Myocardial Infarction Registry-National Institutes of Health, we selected patients who underwent PCI with second-generation drug-eluting stent implantation. The primary outcome was the risk of target lesion failure at 3 years. Among the study population, 1887 patients (21.0%) underwent IVUS-guidance, and 7120 patients (79.0%) underwent angiography-guidance for second-generation drug-eluting stent implantation. IVUS-guided PCI was associated with a significantly lower risk of target lesion failure at 3 years (4.8% versus 8.0%; hazard ratio [HR], 0.59; 95% CI, 0.47 to 0.73; P<0.001) compared with angiography-guided PCI. The difference was driven mainly by a lower risk of cardiac death and target vessel myocardial infarction. The results were consistent after confounder adjustment by multiple sensitivity analyses. Moreover, quartile analysis of volume of IVUS use showed that higher IVUS use was associated with a decreased risk of 3-year target lesion failure (adjusted HR, 0.58; 95% CI, 0.45 to 0.75; P<0.001 for quartile 1 versus 4; P<0.001 for trend comparison across all quartiles). Conclusions In patients with acute myocardial infarction who underwent PCI with second-generation drug-eluting stent implantation, the use of IVUS guidance was associated with a significant reduction in 3-year target lesion failure, mainly driven by hard end points, such as cardiac death and target vessel myocardial infarction.
Files in This Item:
T202201012.pdf Download
DOI
10.1161/JAHA.121.023481
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Byeong Keuk(김병극) ORCID logo https://orcid.org/0000-0003-2493-066X
Kim, Yongcheol(김용철) ORCID logo https://orcid.org/0000-0001-5568-4161
Bae, SungA(배성아) ORCID logo https://orcid.org/0000-0003-1484-4645
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Cho, Deok Kyu(조덕규)
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Hong, Myeong Ki(홍명기) ORCID logo https://orcid.org/0000-0002-2090-2031
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188383
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links