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Expanding the Clinical Spectrum of Multiple Evanescent White Dot Syndrome with Overlapping Multifocal Choroiditis

Authors
 Hyun Goo Kang  ;  Tae Young Kim  ;  Min Kim  ;  Suk Ho Byeon  ;  Sung Soo Kim  ;  Hyoung Jun Koh  ;  Sung Chul Lee  ;  Christopher Seungkyu Lee 
Citation
 OCULAR IMMUNOLOGY AND INFLAMMATION, Vol.30(1) : 81-89, 2022-01 
Journal Title
OCULAR IMMUNOLOGY AND INFLAMMATION
ISSN
 0927-3948 
Issue Date
2022-01
MeSH
Adult ; Choroid ; Choroiditis* / diagnosis ; Female ; Fluorescein Angiography ; Humans ; Multifocal Choroiditis ; Retrospective Studies ; Tomography, Optical Coherence ; White Dot Syndromes* / diagnosis
Keywords
Choriocapillaris ; multifocal choroiditis ; multiple evanescent white dot syndrome ; optical coherence tomography angiography ; white dot syndrome
Abstract
Purpose: To evaluate multifocal evanescent white dot syndrome (MEWDS) patients with and without overlapping multifocal choroiditis (MFC).

Methods: Thirty-four patients diagnosed between November 2008 and August 2018 at 2 hospitals were retrospectively reviewed. Multimodal imaging including optical coherence tomography angiography (OCTA) was assessed.

Results: Twenty-seven (79%) patients were women (overall mean age, 30 years). Five developed MFC lesions in the affected eyes, and one developed MFC in the unaffected fellow eye. Another developed combined MEWDS and MFC in the fellow eye during follow-up. Eyes with MFC had thicker choroids (316.5 and 197.3 µm, respectively; P = .001) at presentation, which became thinner after resolution (P = .043). Those with subfoveal MFC had poor visual prognosis (P = .019). Areas of suspected choriocapillaris flow deficit were identified on OCTA.

Conclusion: Some MEWDS patients may develop overlapping MFC in the same or fellow eyes, presenting with increased choroidal thickness which decreased after resolution.
Full Text
https://www.tandfonline.com/doi/full/10.1080/09273948.2020.1795206
DOI
10.1080/09273948.2020.1795206
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Hyun Goo(강현구) ORCID logo https://orcid.org/0000-0001-8359-9618
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kim, Min(김민) ORCID logo https://orcid.org/0000-0003-1873-6959
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188292
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