Cited 6 times in
Association Between the Severity of Periodontitis and Osteoarthritis in Middle-Aged and Older Patients With Type 2 Diabetes Mellitus: A Nationwide Population-Based Study
DC Field | Value | Language |
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dc.contributor.author | 김형식 | - |
dc.contributor.author | 박혜민 | - |
dc.contributor.author | 손다혜 | - |
dc.contributor.author | 이용제 | - |
dc.contributor.author | 이혜선 | - |
dc.date.accessioned | 2022-03-11T10:57:48Z | - |
dc.date.available | 2022-03-11T10:57:48Z | - |
dc.date.issued | 2022-03 | - |
dc.identifier.issn | 2151-464X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/188074 | - |
dc.description.abstract | Objective: Periodontitis and osteoarthritis are major public health concerns that result in decreased quality of life among middle-aged and older adults. We sought to examine whether the severity of periodontitis is related to osteoarthritis according to the presence of type 2 diabetes mellitus. Methods: This study included 3,527 participants age ≥50 years from the Korean National Health and Nutrition Examination Survey. Periodontitis was assessed using the Community Periodontal Index; severe periodontitis was defined as periodontal tissue forming deep periodontal pockets ≥6-mm depth. Osteoarthritis was defined as Kellgren/Lawrence grade ≥2 on radiographic images of the knee or hip area with joint pain. The odds ratios (ORs) and 95% confidence intervals (95% CIs) for osteoarthritis according to the severity of periodontitis, stratified by type 2 diabetes mellitus, were calculated using multiple logistic regression analyses. Results: Participants with type 2 diabetes mellitus were more likely to have osteoarthritis as the severity of periodontitis increased (nonsevere periodontitis OR 1.23 [95% CI 0.67-2.32]; severe periodontitis OR 3.01 [95% CI 1.51-5.84]) after adjusting for age, sex, body mass index, smoking status, alcohol consumption, regular exercise, education level, household income, hypertension, and frequent tooth-brushing. However, this positive association was not found in individuals without type 2 diabetes mellitus after adjusting for the same covariables. Conclusion: Severe periodontitis was positively and significantly associated with osteoarthritis in middle-aged and older individuals with type 2 diabetes mellitus. Our findings suggest that the oral inflammation manifesting in periodontitis may be at least partly involved in the pathogenesis of osteoarthritis, particularly in patients with type 2 diabetes mellitus. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | John Wiley & Sons | - |
dc.relation.isPartOf | ARTHRITIS CARE & RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Association Between the Severity of Periodontitis and Osteoarthritis in Middle-Aged and Older Patients With Type 2 Diabetes Mellitus: A Nationwide Population-Based Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Orthopedic Surgery (정형외과학교실) | - |
dc.contributor.googleauthor | Hyoung-Sik Kim | - |
dc.contributor.googleauthor | Hye-Min Park | - |
dc.contributor.googleauthor | Haeyoung Kim | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Da-Hye Son | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.identifier.doi | 10.1002/acr.24484 | - |
dc.contributor.localId | A01150 | - |
dc.contributor.localId | A05789 | - |
dc.contributor.localId | A05543 | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J04180 | - |
dc.identifier.eissn | 2151-4658 | - |
dc.identifier.pmid | 33044789 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/acr.24484 | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Cross-Sectional Studies | - |
dc.subject.keyword | Diabetes Mellitus, Type 2 / epidemiology* | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Health Surveys | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Osteoarthritis / epidemiology* | - |
dc.subject.keyword | Osteoarthritis / etiology | - |
dc.subject.keyword | Periodontitis / epidemiology* | - |
dc.subject.keyword | Republic of Korea | - |
dc.subject.keyword | Severity of Illness Index | - |
dc.contributor.alternativeName | Kim, Hyoung Sik | - |
dc.contributor.affiliatedAuthor | 김형식 | - |
dc.contributor.affiliatedAuthor | 박혜민 | - |
dc.contributor.affiliatedAuthor | 손다혜 | - |
dc.contributor.affiliatedAuthor | 이용제 | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.citation.volume | 74 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 403 | - |
dc.citation.endPage | 409 | - |
dc.identifier.bibliographicCitation | ARTHRITIS CARE & RESEARCH, Vol.74(3) : 403-409, 2022-03 | - |
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