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Risk factors for alcohol recidivism after liver transplantation

Authors
 Hyeok Jun Yun  ;  Jae Geun Lee  ;  Hyun Jeong Kim  ;  Dai Hoon Han  ;  Gi Hong Choi  ;  Myoung Soo Kim  ;  Jin Sub Choi  ;  Soon Il Kim  ;  Dong Jin Joo 
Citation
 Annals of Liver Transplantation, Vol.1(1) : 18-23, 2021-05 
Journal Title
Annals of Liver Transplantation
ISSN
 2765-5121 
Issue Date
2021-05
Keywords
Alcohol ; Liver transplantation ; Recidivism ; Survival
Abstract
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Background: Alcoholic liver disease (ALD) has been increasing recently and the second most common indication for liver transplantation (LT) in Korea. Even after LT, alcohol recidivism can be a problem interfering with the patients’ long-term survival and graft function. This study was conducted to analyze the clinical course and preand post-transplantation risk factors for alcohol recidivism in transplant recipients with ALD.
Methods: Of 592 liver transplant recipients, sixty-two patients underwent LT for ALD between Jan 2005 and Dec 2014. We retrospectively collected and analyzed the data from our electrical medical records.
Results: Out of the 62 ALD recipients, 57 patients were male. Their mean age was 52.4±8.3 years. The mean abstinence period of them before transplantation was 17.7±30.0 months. Sixteen recipients (25.8%) showed alcohol recidivism at 15.9±13.7 months after LT. Patients who showed alcohol recidivism had a significantly longer duration of drink before transplantation than non-recidivism patients (35.4±6.3 vs 30.9±9.4 years, respectively, p=0.038). In terms of alcohol consumption, the recidivism group showed more alcohol drinking than the non-recidivism group (123.0±67.2 vs 81.6±61.0 units, respectively, p=0.026). The abstinence period before LT was not significantly different. In the multivariate analysis, the amount of alcohol consumption before transplantation was considered to play a risk factor for alcohol recidivism after transplantation (p=0.05).
Conclusion: Information about duration and consumption of alcohol drink before LT helps to predict alcohol recidivism after LT in patients with ALD, allowing early awareness and specific postoperative care.
Files in This Item:
T202105333.pdf Download
DOI
10.52604/alt.21.0011
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myoung Soo(김명수) ORCID logo https://orcid.org/0000-0002-8975-8381
Kim, Soon Il(김순일) ORCID logo https://orcid.org/0000-0002-0783-7538
Kim, Hyun Jeong(김현정)
Yun, Hyeok Jun(윤혁준) ORCID logo https://orcid.org/0000-0001-6004-0782
Lee, Jae Geun(이재근) ORCID logo https://orcid.org/0000-0002-6722-0257
Joo, Dong Jin(주동진) ORCID logo https://orcid.org/0000-0001-8405-1531
Choi, Gi Hong(최기홍) ORCID logo https://orcid.org/0000-0002-1593-3773
Choi, Jin Sub(최진섭)
Han, Dai Hoon(한대훈) ORCID logo https://orcid.org/0000-0003-2787-7876
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187239
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