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Characterizing right-angled vessel in macular telangiectasia type 2 with structural optical coherence tomography

 Yoo-Ri Chung  ;  Young Ho Kim  ;  Jaeryung Oh  ;  Seong-Woo Kim  ;  Christopher Seungkyu Lee  ;  Cheolmin Yun  ;  Boram Lee  ;  So Min Ahn  ;  Eun Young Choi  ;  Sungmin Jang  ;  Kihwang Lee 
 SCIENTIFIC REPORTS, Vol.11(1) : 17198, 2021-08 
Journal Title
Issue Date
Aged ; Female ; Humans ; Male ; Middle Aged ; Retinal Telangiectasis / diagnostic imaging* ; Retinal Vessels / diagnostic imaging ; Tomography, Optical Coherence / methods*
We investigated the structural findings on spectral-domain optical coherence tomography (SD-OCT) related to the presence of right-angled vessels (RAV) in patients with macular telangiectasia (MacTel) type 2 with severity 3 in Korea. A retrospective multicenter cross-sectional study was conducted in six tertiary hospitals in Korea; the study included 116 MacTel type 2 eyes with severity 3. The SD-OCT findings were compared between eyes with RAV on fundus photography or fluorescein angiography and those without RAV. Logistic regression was performed to determine factors associated with the presence of RAV. Fifty eyes presented with RAV and 61 eyes without RAV. More eyes presented with only inner retinal (IR) cavities on SD-OCT among eyes without RAV than among those with RAV (P < 0.001). However, eyes with RAV presented with IR disorganization, outer retinal (OR) cavity, and ellipsoid zone (EZ) disruption more frequently than eyes without RAV did (all P < 0.001). These SD-OCT findings were significantly associated with the presence of RAV. The presence of RAV was closely related to IR disorganization, OR cavities, and EZ disruption on SD-OCT. These findings suggest an advanced phase of MacTel type 2.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Choi, Eun Young(최은영) ORCID logo https://orcid.org/0000-0002-1668-6452
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