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Nutritional effects according to reconstructional methods after total gastrectomy

Authors
 Jin Sik Min  ;  Seung Ho Choi  ;  Sung Hoon Noh  ;  Myung Wook Kim 
Citation
 YONSEI MEDICAL JOURNAL, Vol.36(1) : 9-14, 1995-03 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
1995-03
MeSH
Anastomosis, Roux-en-Y ; Animal Nutritional Physiological Phenomena* ; Animals ; Dogs ; Duodenostomy ; Esophagostomy ; Gastrectomy* ; Jejunostomy
Keywords
Nutrition-Reconstruction-Total gastrectomy
Abstract
Malnutrition and weight loss after total gastrectomy is one of the major concerns of surgeons. In order to improve the nutritional status in these patients, many surgeons have tried to restore the duodenal passage as reconstructive procedure but debates have been continued. So we investigated weight change, postprandial serum secretin response and fecal fat amount to evaluate the esophagojejunoduodenostomy after which the duodenal passage was restored. Total gastrectomized dogs showed significant weight loss and all experimental animals except sham operation died between five and eight weeks after the operation. Serum secretin concentration after esophagojejunoduodenostomy increased significantly from a mean fasting value of 100 ± 12.5 pg/mL to a mean peak of 142 ± 22.5 pg/mL at 40 minutes and returned to the fasting level at 120 minutes postprandially. But fasting and postprandial serum secretin concentration in patients following Roux-en Y esophagojejunostomy were fluctuated irregularly. The amount of fecal fat in esophagojejunoduodenostomy was 5.3 ± 1.2 gm/100 gm stool, which was not different from that of the control group but in Roux-en Y esophagojejunostomy it was 28.1 ± 4.1 gm/100 gm stool which was much higher than that observed in esophagojejunoduodenostomy and in control group. These results suggest that esophagojejunoduodenostomy is superior to Roux-en Y esophagojejunostomy in respect to pancreatic secretory function and fat absorption.
Files in This Item:
T199501786.pdf Download
DOI
10.3349/ymj.1995.36.1.9
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Noh, Sung Hoon(노성훈) ORCID logo https://orcid.org/0000-0003-4386-6886
Choi, Seung Ho(최승호) ORCID logo https://orcid.org/0000-0002-9872-3594
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/186511
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