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한국인 비감염성 포도막염 환자에서 유리체강내 덱사메타손 이식제의 치료 효과 분석

Other Titles
 Therapeutic Efficacy of Intravitreal Dexamethasone Implant in Korean Patients with Non-infectious Uveitis 
Authors
 한재용  ;  이동현  ;  김정동  ;  최은영  ;  김민 
Citation
 JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, Vol.62(6) : 798-805, 2021-06 
Journal Title
JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY(대한안과학회지)
ISSN
 0378-6471 
Issue Date
2021-06
Keywords
Intravitreal injection ; Ozurdex ; Uveitis
Abstract
Purpose
To evaluate the therapeutic efficacy and safety of intravitreal dexamethasone implant in non-infectious uveitis (divided into anterior, intermediate, posterior, and panuveitis types).
Methods
The medical records of patients who received intravitreal dexamethasone implants between June 2013 and January 2018 at a tertiary referral hospital were analyzed retrospectively.
Results
A total of 38 eyes of 36 patients were included. All patients were diagnosed with non-infectious uveitis and received intravitreal dexamethasone implants. The mean age was 55.6 years, and 18 (50.0%) patients were male. In total, 6 (15.8%) eyes were diagnosed with anterior uveitis, 5 (13.2%) with intermediate uveitis, 16 (42.1%) with posterior uveitis, and 11 (28.9%) with panuveitis. Patients with all types of uveitis showed significant improvement in clinical outcomes after intravitreal dexamethasone implant. Three eyes showed increased intraocular pressure, while four showed cataract progression and thus received cataract extraction after injection. Seventeen (44.7%) eyes relapsed an average of 1.18 ± 0.39 times and received additional treatments.
Conclusions
Non-infectious uveitis patients showed significant improvement in clinical outcomes after intravitreal dexamethasone implant injection. However, care is required during injection due to the risk of recurrence, as well as side effects such as increased intraocular pressure and cataract progression.
Files in This Item:
T202104077.pdf Download
DOI
10.3341/jkos.2021.62.6.798
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min(김민) ORCID logo https://orcid.org/0000-0003-1873-6959
Choi, Eun Young(최은영) ORCID logo https://orcid.org/0000-0002-1668-6452
Han, Jae Yong(한재용)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185411
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