폐경 이후 여성에서 Reproductive Factors와 심뇌혈관 질환과의 연관성: 국민건강영양조사 2016–2017년도 자료를 이용한 단면연구
Other Titles
Association between Reproductive Factors and Cardiovascular Disease Risk in Post-Menopausal Women: Cross-Sectional Study from the 2016–2017 Korea National Health and Nutrition Examination Survey
Authors
강지연 ; 김지은 ; 유난이 ; 강희철
Citation
Korean Journal of Family Practice(가정의학), Vol.10(3) : 182-191, 2020-06
Background: Reproductive factors such as childbirth, gravidity, age of menarche, breastfeeding, and use of oral contraceptives could affect the risk of
cardiovascular disease in women. This study aimed to investigate the relationship between reproductive factors and cardiovascular disease in
postmenopausal women in Korea.
Methods: This study included 2,310 women aged ≥45 years who experienced natural menopause and participated in the 7th Korea National Health
and Nutrition Examination Survey (2016–2017). Cardiovascular disease was defined as myocardial infarction, angina, and stroke. Coronary heart
disease was defined as myocardial infarction and angina. Logistic regression was performed to calculate the odds ratio of cardiovascular disease
with respect to each reproductive factor.
Results: Women who breastfed for longer duration (≥24 months) group had a 3-fold higher risk of cardiovascular disease and 4–5-fold higher risk of
coronary heart disease than those in the non-breastfeeding group. One-time pregnancy was associated with a higher risk of coronary heart disease
than gravidity of 6. Early menarche (≤11 years of age) was associated with a high risk of stroke. Women who had a history of using oral
contraceptives were at low risk of stroke.
Conclusion: Breastfeeding, low gravidity, and early menarche were associated with an increased risk of cardiovascular disease, whereas use of oral
contraceptives was associated with reduced risk of stroke. However, some of these results were different from previous reports. Therefore, further
studies are needed to identify the relationship between reproductive factors and cardiovascular disease in women.