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유전자 CYP2C9 및 VKORC1 변이로 인한 와파린 과민성을 동반한 가와사키병 환아 1례

Other Titles
 A child with Kawasaki disease and genetic warfarin sensitivity from CYP2C9 and VKORC1 gene variants 
Authors
 이명섭  ;  은영민 
Citation
 Pediatric Emergency Medicine Journal, Vol.7(2) : 140-144, 2020-12 
Journal Title
Pediatric Emergency Medicine Journal
ISSN
 2383-4897 
Issue Date
2020-12
Keywords
Anticoagulants ; Coronary Aneurysm ; Cytochrome P-450 Enzyme System ; Mucocutaneous Lymph Node Syndrome ; Warfarin
Abstract
Kawasaki disease (KD) is a common febrile disease in East Asia. Because KD with coronary artery aneurysm (CAA) may predispose to thrombosis, children with KD-associated CAA may need anticoagulation in addition to aspirin. In this report, we describe a 6-year-old girl with KD and CAA who was found to have unexpected warfarin-induced coagulopathy caused by CYP2C9 and VKORC1 genotype variants, which affect warfarin metabolism.
Files in This Item:
T999202332.pdf Download
DOI
10.22470/pemj.2020.00143
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Eun, Lucy Youngmin(은영민) ORCID logo https://orcid.org/0000-0002-4577-3168
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185015
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