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Metabolic activity assessment by 18 F-fluorodeoxyglucose positron emission tomography in patients with hepatocellular carcinoma undergoing Yttrium-90 transarterial radioembolization
DC Field | Value | Language |
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dc.contributor.author | 김경민 | - |
dc.contributor.author | 김도영 | - |
dc.contributor.author | 원종윤 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 이혜원 | - |
dc.date.accessioned | 2021-09-29T01:22:08Z | - |
dc.date.available | 2021-09-29T01:22:08Z | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184331 | - |
dc.description.abstract | Background and aim: 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is a functional image technique that can inform clinical decisions related to prognosis. We investigated the predictive role of 18 F-fluorodeoxyglucose PET/CT in patients with hepatocellular carcinoma (HCC) undergoing Yttrium-90 (Y-90) transarterial radioembolization (TARE). Methods: Patients with HCC treated with TARE and pre-TARE PET/CT scan were recruited between 2009 and 2013. Maximum standardized uptake value and tumor-to-non-tumorous liver uptake ratio (TLR) were measured. Tumor response was evaluated in accordance with modified RECIST criteria at 3-month intervals after Y-90 TARE. Results: Forty patients were included in the final analysis. The median age was 56.5 years and male predominant. Disease control in treated lesion was achieved in 82.5% (n = 33) of patients. During median 18.3-month follow-up, 27.5% (n = 11) of patients achieved progression-free survival. The cutoff of TLR, which was related to the median value, did not affect disease control rate, progression-free survival, and overall survival in patients with Y-90 TARE. Conclusions: The TLR-based stratification may be a simple method, but our study did not show the usefulness in predicting prognosis in HCC patients with Y-90 TARE. Further studies with large number of patients are needed. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Metabolic activity assessment by 18 F-fluorodeoxyglucose positron emission tomography in patients with hepatocellular carcinoma undergoing Yttrium-90 transarterial radioembolization | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Do Young Kim | - |
dc.contributor.googleauthor | Hye Won Lee | - |
dc.contributor.googleauthor | Wonseok Kang | - |
dc.contributor.googleauthor | Gyoung Min Kim | - |
dc.contributor.googleauthor | Jong Yun Won | - |
dc.contributor.googleauthor | Mijin Yun | - |
dc.identifier.doi | 10.1111/jgh.15357 | - |
dc.contributor.localId | A00296 | - |
dc.contributor.localId | A00385 | - |
dc.contributor.localId | A02443 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A03318 | - |
dc.relation.journalcode | J01417 | - |
dc.identifier.eissn | 1440-1746 | - |
dc.identifier.pmid | 33226706 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/jgh.15357 | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | Positron emission tomography | - |
dc.subject.keyword | Yttrium-90 | - |
dc.contributor.alternativeName | Kim, Gyoung Min | - |
dc.contributor.affiliatedAuthor | 김경민 | - |
dc.contributor.affiliatedAuthor | 김도영 | - |
dc.contributor.affiliatedAuthor | 원종윤 | - |
dc.contributor.affiliatedAuthor | 윤미진 | - |
dc.contributor.affiliatedAuthor | 이혜원 | - |
dc.citation.volume | 36 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1679 | - |
dc.citation.endPage | 1684 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.36(6) : 1679-1684, 2021-06 | - |
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