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A rare acantholytic variant of squamous cell carcinoma of the maxilla: A case report and literature review

Authors
 Jo-Eun Kim  ;  Chena Lee  ;  Kyu-Young Oh  ;  Kyung-Hoe Huh 
Citation
 MEDICINE, Vol.99(32) : e21631, 2020-08 
Journal Title
MEDICINE
ISSN
 0025-7974 
Issue Date
2020-08
MeSH
Acantholysis / complications ; Acantholysis / diagnosis* ; Biopsy / methods ; Carcinoma, Squamous Cell / diagnosis* ; Carcinoma, Squamous Cell / physiopathology ; Female ; Humans ; Maxilla / abnormalities* ; Maxilla / radiation effects ; Middle Aged ; Radiotherapy / methods
Abstract
Rationale: Acantholytic squamous cell carcinoma (ASCC) is an uncommon histopathologic variant of squamous cell carcinoma (SCC), which is the most common malignancy of the oral cavity. Though ASCC showed poor prognosis, the exact diagnosis is challenging. Patients concerns: A 59-year-old female patient with 1-month long symptoms of pain and burning sensation in the right maxilla. Diagnoses: Incisional biopsy in the maxilla established the pathologic diagnosis of SCC. Intervention: The patient underwent mass resection with near total maxillectomy. Outcomes: The final diagnosis through the microscopic examination was ASCC. Palliative chemotherapy was done to relive the symptoms after the recurrence, however, the patient died of the disease at 8 months after her initial presentation. Lessons: Special attention should be paid to this variant of SCC because most patients with ASCC have a very poor prognosis.
Files in This Item:
T202007082.pdf Download
DOI
10.1097/MD.0000000000021631
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Radiology (영상치의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Chena(이채나) ORCID logo https://orcid.org/0000-0002-8943-4192
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/183811
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