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황반원공 환자에서 유리체내 ascorbic acid 농도

Other Titles
 The Concentration of Ascorbic acid in Vitreous of Macular Hole Patients 
Authors
 진희승  ;  권오웅 
Citation
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.37(3) : 491-495, 1996-07 
Journal Title
JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY(대한안과학회지)
ISSN
 0378-6471 
Issue Date
1996-07
Keywords
Ascorbic acid ; Macular hole ; Vitreous
Abstract
The concentration of ascorbic acid in human aqueous is greater than that of blood. The function of ascorbic acid in aqueous humor is an antioxidant which contributes in absorption of ultraviolet and protection of ocular tissue from free radical damage. Ascorbic acid is also found in vitreous and the concentration is very high in human. However the function is yet not verified. The purpose of this study is to measure the ascorbic acid concentration of vitreous in macular hole patients. Seven patients who underwent trans pars plana vitrectomy for macular hole were selected and small amount of serum, aqueous humor and vitreous were taken. The concentration of ascorbic acid was measured from serum, aqueous humor and vitreous by high performance liquid chromatography. The average concentrations of ascorbic acid were 24.1±13.7μg/ml in serum, 144.0±34.5μg/ml in aqueous humor and 110.2±34.6μg/ml in vitreous. The concentration of ascorbic acid in vitreous was 5∼6 times higher than in serum but slighly lower than in aqueous humor. In conclusion the ascorbic acid concentration of vitreous in macular hole patients was lower than normals
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Oh Woong(권오웅)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/183182
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