0 45

Cited 0 times in

Efficacy of a povidone-iodine foam dressing (Betafoam) on diabetic foot ulcer

Authors
 Heui C Gwak  ;  Seung H Han  ;  Jinwoo Lee  ;  Sejin Park  ;  Ki-Sun Sung  ;  Hak-Jun Kim  ;  Dongil Chun  ;  Kyungmin Lee  ;  Jae-Hoon Ahn  ;  Kyunghee Kwak  ;  Hyung-Jin Chung 
Citation
 INTERNATIONAL WOUND JOURNAL, Vol.17(1) : 91-99, 2020-02 
Journal Title
INTERNATIONAL WOUND JOURNAL
ISSN
 1742-4801 
Issue Date
2020-02
MeSH
Adult ; Aged ; Aged, 80 and over ; Bandages, Hydrocolloid* ; Diabetes Complications / drug therapy* ; Diabetic Foot / drug therapy* ; Female ; Humans ; Male ; Middle Aged ; Povidone-Iodine / therapeutic use* ; Republic of Korea ; Wound Healing / drug effects* ; Wound Healing / physiology* ; Wound Infection / drug therapy* ; Young Adult
Keywords
Betafoam ; Medifoam ; diabetic foot ulcer ; povidone-iodine ; wound healing
Abstract
This study aimed to assess the efficacy of a new povidone-iodine (PVP-I) foam dressing (Betafoam) vs foam dressing (Medifoam) for the management of diabetic foot ulcers. This study was conducted between March 2016 and September 2017 at 10 sites in Korea. A total of 71 patients (aged ≥19 years) with type 1/2 diabetes and early-phase diabetic foot ulcers (Wagener classification grade 1/2) were randomised to treatment with PVP-I foam dressing or foam dressing for 8 weeks. Wound healing, wound infection, patient satisfaction, and adverse events (AEs) were assessed. The PVP-I foam and foam dressing groups were comparable in the proportion of patients with complete wound healing within 8 weeks (44.4% vs 42.3%, P = .9191), mean (±SD) number of days to complete healing (31.00 ± 15.07 vs 33.27 ± 12.60 days; P = .6541), and infection rates (11.1% vs 11.4%; P = 1.0000). Median satisfaction score (scored from 0 to 10) at the final visit was also comparable between groups (10 vs 9, P = .2889). There was no significant difference in AE incidence (27.8% vs 17.1%, P = .2836), and none of the reported AEs had a causal relationship with the dressings. The results of this study suggest that PVP-I foam dressing has wound-healing efficacy comparable with foam dressing, with no notable safety concerns. This study was funded by Mundipharma Korea Ltd and registered at ClinicalTrials.gov (identifier NCT02732886).
Full Text
https://onlinelibrary.wiley.com/doi/10.1111/iwj.13236
DOI
10.1111/iwj.13236
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Jin Woo(이진우) ORCID logo https://orcid.org/0000-0002-0293-9017
Han, Seung Hwan(한승환) ORCID logo https://orcid.org/0000-0002-7975-6067
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182573
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links