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Efficacy of a povidone-iodine foam dressing (Betafoam) on diabetic foot ulcer

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dc.contributor.author이진우-
dc.contributor.author한승환-
dc.date.accessioned2021-05-21T16:49:01Z-
dc.date.available2021-05-21T16:49:01Z-
dc.date.issued2020-02-
dc.identifier.issn1742-4801-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182573-
dc.description.abstractThis study aimed to assess the efficacy of a new povidone-iodine (PVP-I) foam dressing (Betafoam) vs foam dressing (Medifoam) for the management of diabetic foot ulcers. This study was conducted between March 2016 and September 2017 at 10 sites in Korea. A total of 71 patients (aged ≥19 years) with type 1/2 diabetes and early-phase diabetic foot ulcers (Wagener classification grade 1/2) were randomised to treatment with PVP-I foam dressing or foam dressing for 8 weeks. Wound healing, wound infection, patient satisfaction, and adverse events (AEs) were assessed. The PVP-I foam and foam dressing groups were comparable in the proportion of patients with complete wound healing within 8 weeks (44.4% vs 42.3%, P = .9191), mean (±SD) number of days to complete healing (31.00 ± 15.07 vs 33.27 ± 12.60 days; P = .6541), and infection rates (11.1% vs 11.4%; P = 1.0000). Median satisfaction score (scored from 0 to 10) at the final visit was also comparable between groups (10 vs 9, P = .2889). There was no significant difference in AE incidence (27.8% vs 17.1%, P = .2836), and none of the reported AEs had a causal relationship with the dressings. The results of this study suggest that PVP-I foam dressing has wound-healing efficacy comparable with foam dressing, with no notable safety concerns. This study was funded by Mundipharma Korea Ltd and registered at ClinicalTrials.gov (identifier NCT02732886).-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish, French(Summary), German(Summary), Italian(Summary), Spanish(Summary)-
dc.publisherBlackwell Pub.-
dc.relation.isPartOfINTERNATIONAL WOUND JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHBandages, Hydrocolloid*-
dc.subject.MESHDiabetes Complications / drug therapy*-
dc.subject.MESHDiabetic Foot / drug therapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPovidone-Iodine / therapeutic use*-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHWound Healing / drug effects*-
dc.subject.MESHWound Healing / physiology*-
dc.subject.MESHWound Infection / drug therapy*-
dc.subject.MESHYoung Adult-
dc.titleEfficacy of a povidone-iodine foam dressing (Betafoam) on diabetic foot ulcer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Orthopedic Surgery (정형외과학교실)-
dc.contributor.googleauthorHeui C Gwak-
dc.contributor.googleauthorSeung H Han-
dc.contributor.googleauthorJinwoo Lee-
dc.contributor.googleauthorSejin Park-
dc.contributor.googleauthorKi-Sun Sung-
dc.contributor.googleauthorHak-Jun Kim-
dc.contributor.googleauthorDongil Chun-
dc.contributor.googleauthorKyungmin Lee-
dc.contributor.googleauthorJae-Hoon Ahn-
dc.contributor.googleauthorKyunghee Kwak-
dc.contributor.googleauthorHyung-Jin Chung-
dc.identifier.doi10.1111/iwj.13236-
dc.contributor.localIdA03230-
dc.contributor.localIdA04305-
dc.relation.journalcodeJ01178-
dc.identifier.eissn1742-481X-
dc.identifier.pmid31773882-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1111/iwj.13236-
dc.subject.keywordBetafoam-
dc.subject.keywordMedifoam-
dc.subject.keyworddiabetic foot ulcer-
dc.subject.keywordpovidone-iodine-
dc.subject.keywordwound healing-
dc.contributor.alternativeNameLee, Jin Woo-
dc.contributor.affiliatedAuthor이진우-
dc.contributor.affiliatedAuthor한승환-
dc.citation.volume17-
dc.citation.number1-
dc.citation.startPage91-
dc.citation.endPage99-
dc.identifier.bibliographicCitationINTERNATIONAL WOUND JOURNAL, Vol.17(1) : 91-99, 2020-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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