Purpose: This study aimed to investigate the computed tomography and magnetic resonance imaging features of
giant cell tumors in the temporomandibular joint region to facilitate accurate diagnoses.
Materials and Methods: From October 2007 to June 2020, 6 patients (2 men and 4 women) at Yonsei University
Dental Hospital had histopathologically proven giant cell tumors in the temporomandibular joint. Their computed
tomography and magnetic resonance imaging findings were reviewed retrospectively, and the cases were classified
into 3 types based on the tumor center and growth pattern observed on the radiologic findings.
Results: The age of the 6 patients ranged from 25 to 53 years. Trismus was found in 5 of the 6 cases. One case
recurred. The mean size of the tumors, defined based on their greatest diameter, was 32 mm (range, 15-41 mm). The
characteristic features of all cases were a heterogeneously-enhancing tumorous mass with a lobulated margin on
computed tomographic images and internal multiplicity of signal intensity on T2-weighted magnetic resonance images.
According to the site of origin, 3 tumors were bone-centered, 2 were soft tissue-centered, and 1 was peri-articular.
Conclusion: Computed tomography and magnetic resonance imaging yielded a tripartite classification of giant cell
tumors of the temporomandibular joint according to their location on imaging. This study could help clinicians in
the differential diagnosis of giant cell tumors and assist in proper treatment planning for tumorous diseases of the
temporomandibular joint.