Cited 4 times in
Non-Alcoholic Fatty Liver Disease Is an Independent Risk Factor for LDL Cholesterol Target Level
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권유진 | - |
dc.contributor.author | 이용제 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 조아라 | - |
dc.date.accessioned | 2021-04-29T17:19:12Z | - |
dc.date.available | 2021-04-29T17:19:12Z | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 1661-7827 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182282 | - |
dc.description.abstract | Although patients with non-alcoholic fatty liver disease (NAFLD) face a higher risk of cardiovascular disease (CVD), it is not known whether people with NAFLD are less likely to achieve optimal management of low-density lipoprotein (LDL) cholesterol than those without NAFLD. We aimed to investigate the longitudinal effect of NAFLD on the management of LDL cholesterol in 5610 adults from the Korean Genome and Epidemiology Study. Participants were classified into NAFLD and normal groups. Non-achievement of the target LDL cholesterol level was set according to one's cardiovascular disease (CVD) risk level. The estimated proportion of individuals who did not achieve their LDL cholesterol targets was higher in the NAFLD group than in the normal group during the follow-up period of 12 years in a generalized estimation equation model. Multivariable Cox regression analysis revealed a hazard ratio and 95% confidence interval for incident non-achievement of one's LDL cholesterol target of 1.196 (1.057-1.353) in the NAFLD group (p = 0.005). We found that NAFLD was significantly related to non-achievement of LDL cholesterol targets in this prospective cohort study. Prevention and proper management of NAFLD have important health implications for the prevention of CVD. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Non-Alcoholic Fatty Liver Disease Is an Independent Risk Factor for LDL Cholesterol Target Level | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Jun-Hyuk Lee | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | A-Ra Cho | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.contributor.googleauthor | Yu-Jin Kwon | - |
dc.identifier.doi | 10.3390/ijerph18073442 | - |
dc.contributor.localId | A04882 | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A05183 | - |
dc.relation.journalcode | J01111 | - |
dc.identifier.eissn | 1660-4601 | - |
dc.identifier.pmid | 33810315 | - |
dc.subject.keyword | cardiovascular disease | - |
dc.subject.keyword | low-density lipoprotein cholesterol | - |
dc.subject.keyword | non-alcoholic fatty liver disease | - |
dc.contributor.alternativeName | Kwon, Yu-Jin | - |
dc.contributor.affiliatedAuthor | 권유진 | - |
dc.contributor.affiliatedAuthor | 이용제 | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.contributor.affiliatedAuthor | 조아라 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 3442 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.18(7) : 3442, 2021-03 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.