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A prospective study on the use of ultralow-dose computed tomography with iterative reconstruction for the follow-up of patients liver and renal abscess

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dc.contributor.author구남수-
dc.contributor.author김명진-
dc.contributor.author박미숙-
dc.contributor.author서니은-
dc.contributor.author염준섭-
dc.contributor.author정용은-
dc.contributor.author최준용-
dc.date.accessioned2021-04-29T17:03:37Z-
dc.date.available2021-04-29T17:03:37Z-
dc.date.issued2021-02-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182161-
dc.description.abstractBackground: Radiation dose reduction is a major concern in patients who undergo computed tomography (CT) to follow liver and renal abscess. Objectives: The purpose of this study is to investigate the feasibility of ultralow-dose CT with iterative reconstruction (IR) to follow patients with liver and renal abscess. Methods: This prospective study included 18 patients who underwent ultralow-dose CT with IR to follow abscesses (liver abscesses in 10 patients and renal abscesses in 8 patients; ULD group). The control group consisted of 14 patients who underwent follow-up standard-dose CT for liver abscesses during the same period. The objective image noise was evaluated by measuring standard deviation (SD) in the liver and subcutaneous fat to select a specific IR for qualitative analysis. Two radiologists independently evaluated subjective image quality, noise, and diagnostic confidence to evaluate abscess using a five-point Likert scale. Qualitative parameters were compared between the ULD and control groups with the Mann-Whitney U test. Results: The mean CT dose index volume and dose length product of standard-dose CT were 8.7 ± 1.8 mGy and 555.8 ± 142.8 mGy·cm, respectively. Mean dose reduction of ultralow-dose CT was 71.8% compared to standard-dose CT. After measuring SDs, iDose level 5, which showed similar SD to standard-dose CT in both the subcutaneous fat and liver (P = 0.076, and P = 0.124), was selected for qualitative analysis. Ultralow-dose CT showed slightly worse subjective image quality (P < 0.001 for reader 1, and P = 0.005 for reader 2) and noise (P = 0.004 for reader 1, and P = 0.001 for reader 2) than standard-dose CT. However, the diagnostic confidence of ultralow-dose CT for evaluating abscess was comparably excellent to standard-dose CT (P = 0.808 for reader 1, and P = 0.301 for reader 2). Conclusions: Ultralow-dose CT with IR can be used in the follow-up of liver and renal abscess with comparable diagnostic confidence.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleA prospective study on the use of ultralow-dose computed tomography with iterative reconstruction for the follow-up of patients liver and renal abscess-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorNieun Seo-
dc.contributor.googleauthorMi-Suk Park-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorJoon-Sup Yeom-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.contributor.googleauthorYong Eun Chung-
dc.contributor.googleauthorNam Su Ku-
dc.identifier.doi10.1371/journal.pone.0246532-
dc.contributor.localIdA00189-
dc.contributor.localIdA00426-
dc.contributor.localIdA01463-
dc.contributor.localIdA01874-
dc.contributor.localIdA02353-
dc.contributor.localIdA03662-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid33577561-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김명진-
dc.contributor.affiliatedAuthor박미숙-
dc.contributor.affiliatedAuthor서니은-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor정용은-
dc.contributor.affiliatedAuthor최준용-
dc.citation.volume16-
dc.citation.number2-
dc.citation.startPagee0246532-
dc.identifier.bibliographicCitationPLOS ONE, Vol.16(2) : e0246532, 2021-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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