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Hyperattenuating lesions after mechanical thrombectomy in acute ischaemic stroke: factors predicting symptomatic haemorrhage and clinical outcomes

DC FieldValueLanguage
dc.contributor.author김동준-
dc.contributor.author김병문-
dc.contributor.author김영대-
dc.contributor.author남효석-
dc.contributor.author안성수-
dc.contributor.author이승구-
dc.contributor.author허지회-
dc.date.accessioned2021-04-29T16:43:50Z-
dc.date.available2021-04-29T16:43:50Z-
dc.date.issued2021-01-
dc.identifier.issn0009-9260-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181986-
dc.description.abstractAim: To evaluate the clinical significance of hyperattenuating lesions on CT after mechanical thrombectomy for acute ischaemic stroke, and to identify imaging factors that predict symptomatic haemorrhage and unfavourable outcomes. Materials and methods: Seventy-eight patients with acute ischaemic stroke in the anterior circulation who underwent mechanical thrombectomy were evaluated. All patients underwent post-interventional unenhanced computed tomography (CT) within 24 h and follow-up CT or magnetic resonance imaging (MRI) within 7 days. Baseline characteristics and clinical outcomes were compared between patients with and without hyperattenuating lesions. In patients with hyperattenuating lesions, clinical and imaging factors that predict symptomatic haemorrhage and unfavourable outcomes were determined. Results: Fifty-six of 78 patients (71.8%) demonstrated hyperattenuating lesions on post-interventional CT. Patients with hyperattenuating lesions showed lower Alberta Stroke Program Early CT score (ASPECTS), persistent/symptomatic haemorrhage, and unfavourable outcomes than those without. In patients with hyperattenuating lesions, larger hyperattenuating lesion volume (>21.3 ml; OR, 55.60, p<0.001) and perilesional oedema (OR, 46.04, p=0.015) were independent factors predicting symptomatic haemorrhage. Older age (OR, 1.2, p=0.006) and lower ASPECTS (OR, 0.45, p=0.046) were independent factors predicting unfavourable outcomes in patients with hyperattenuating lesions. Adding the volume of the hyperattenuating lesion to age and ASPECTS increased the predictive performance of unfavourable outcomes (area under the curve 0.874 versus 0.934, p=0.043). Conclusions: Hyperattenuating lesions on post-interventional CT are associated with increased risk of symptomatic haemorrhage and unfavourable outcomes. Larger hyperattenuating lesion volume is an independent factor of symptomatic haemorrhage and it has added predictive value for unfavourable outcomes.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherBlackwell Scientific Publications Ltd-
dc.relation.isPartOfCLINICAL RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleHyperattenuating lesions after mechanical thrombectomy in acute ischaemic stroke: factors predicting symptomatic haemorrhage and clinical outcomes-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorS Bae-
dc.contributor.googleauthorS S Ahn-
dc.contributor.googleauthorB M Kim-
dc.contributor.googleauthorD J Kim-
dc.contributor.googleauthorY D Kim-
dc.contributor.googleauthorH S Nam-
dc.contributor.googleauthorJ H Heo-
dc.contributor.googleauthorS-K Lee-
dc.identifier.doi10.1016/j.crad.2020.08.021-
dc.contributor.localIdA00410-
dc.contributor.localIdA00498-
dc.contributor.localIdA00702-
dc.contributor.localIdA01273-
dc.contributor.localIdA02234-
dc.contributor.localIdA02912-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ00610-
dc.identifier.eissn1365-229X-
dc.identifier.pmid32950255-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0009926020303731-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.affiliatedAuthor김동준-
dc.contributor.affiliatedAuthor김병문-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor안성수-
dc.contributor.affiliatedAuthor이승구-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume76-
dc.citation.number1-
dc.citation.startPage80.e15-
dc.citation.endPage80.e23-
dc.identifier.bibliographicCitationCLINICAL RADIOLOGY, Vol.76(1) : 80.e15-80.e23, 2021-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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