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Additive prognostic value of red cell distribution width over late gadolinium enhancement on CMR in patients with non-ischemic dilated cardiomyopathy

DC FieldValueLanguage
dc.contributor.author김영진-
dc.contributor.author이혜정-
dc.contributor.author정보영-
dc.date.accessioned2021-01-19T08:09:35Z-
dc.date.available2021-01-19T08:09:35Z-
dc.date.issued2020-06-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181486-
dc.description.abstractElevated red cell distribution width (RDW) and late gadolinium enhancement on cardiac magnetic resonance (LGE-CMR) are both poor prognostic factors. This study examined the relationship between RDW and LGE-CMR characteristics in patients with non-ischemic dilated cardiomyopathy (NICM), and investigated whether the additive prognostic value of RDW as an integrative systemic factor over LGE-CMR exists or not. A total of consecutive 378 patients who underwent CMR at two general hospitals in South Korea were retrospectively analyzed. The primary endpoint was a composite of all-cause death, hospitalizations due to worsening heart failure and major arrhythmic events. During a mean follow-up period of 40.8 months, 151 (39.9%) patients experienced primary endpoints. The RDW value was significantly higher in patients with LGE than in those without LGE (13.7 ± 1.5% vs. 13.3 ± 1.4%, p = 0.034), but it was not associated with the extent or distribution patterns of the LGE. Addition of RDW into the model with clinical risk factors and LGE-CMR characteristics led to a significant improvement in the prediction of worse outcomes (χ2 increased from 73 to 82; p = 0.023). RDW could provide incremental predictive value for adverse clinical events beyond LGE-CMR data in NICM patients.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHCardiomyopathy, Dilated / pathology*-
dc.subject.MESHContrast Media / administration & dosage-
dc.subject.MESHDeath, Sudden, Cardiac / pathology-
dc.subject.MESHErythrocyte Indices / physiology*-
dc.subject.MESHErythrocytes / physiology*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGadolinium / administration & dosage*-
dc.subject.MESHHeart Failure / pathology-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging, Cine / methods-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHStroke Volume / physiology-
dc.subject.MESHVentricular Dysfunction, Left / pathology-
dc.subject.MESHVentricular Function, Left / physiology-
dc.titleAdditive prognostic value of red cell distribution width over late gadolinium enhancement on CMR in patients with non-ischemic dilated cardiomyopathy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorJeong-Eun Yi-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorYookyung Kim-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorJunbeom Park-
dc.identifier.doi10.1038/s41598-020-66198-0-
dc.contributor.localIdA00727-
dc.contributor.localIdA03320-
dc.contributor.localIdA03320-
dc.contributor.localIdA03609-
dc.contributor.localIdA03609-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid32513998-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.affiliatedAuthor김영진-
dc.contributor.affiliatedAuthor이혜정-
dc.contributor.affiliatedAuthor이혜정-
dc.contributor.affiliatedAuthor정보영-
dc.contributor.affiliatedAuthor정보영-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPage9212-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.10(1) : 9212, 2020-06-
dc.identifier.rimsid67237-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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