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Association of optimal blood pressure with mortality in patients taking antihypertensive medications

DC FieldValueLanguage
dc.contributor.author손다혜-
dc.contributor.author이지원-
dc.contributor.author이혜선-
dc.contributor.author장혁재-
dc.date.accessioned2021-01-19T07:41:43Z-
dc.date.available2021-01-19T07:41:43Z-
dc.date.issued2020-11-
dc.identifier.issn1524-6175-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181292-
dc.description.abstractWe investigated the relationship between blood pressure (BP) and mortality in patients taking antihypertensive medications in the Korean using data from the 2007-2015 Korean National Health and Nutrition Examination Surveys. A total of 6601 patients aged 30-74 years were included. Systolic BP (SBP) and diastolic BP (DBP) were both divided into four groups as follows: SBP < 120, 120 ≤ SBP ≤ 129 130 ≤ SBP ≤ 139, and SBP ≥ 140; DBP < 70, 70 ≤ DBP ≤ 79, 80 ≤ DBP ≤ 89, and DBP ≥ 90. The survival rates and hazard ratios were evaluated using Kaplan-Meier curves and multivariable Cox regression analyses. To evaluate the predictability of all-cause mortality according to SBP and/or DBP, we calculated Harrell's concordance-index. The lowest DBP group had a high risk of mortality regardless of the SBP status. The group with DBP < 70 mm Hg and SBP ≥ 140 mm Hg showed the highest mortality. The discriminatory ability calculated using Harrell's C-indexes was greater for the combination of SBP and DBP compared to DBP or SBP alone. These results suggest that it is more effective to simultaneously evaluate the effect of SBP and DBP to predict mortality; clinicians should manage DBP < 70 mm Hg when treating hypertensive patients.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherWiley Periodicals Inc.-
dc.relation.isPartOfJOURNAL OF CLINICAL HYPERTENSION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAssociation of optimal blood pressure with mortality in patients taking antihypertensive medications-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학교실)-
dc.contributor.googleauthorDong-Ho Yun-
dc.contributor.googleauthorHye-Sun Lee-
dc.contributor.googleauthorWon-Jun Choi-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorDa-Hye Son-
dc.contributor.googleauthorJi-Won Lee-
dc.identifier.doi10.1111/jch.14034-
dc.contributor.localIdA05543-
dc.contributor.localIdA03203-
dc.contributor.localIdA03203-
dc.contributor.localIdA03312-
dc.contributor.localIdA03312-
dc.contributor.localIdA03490-
dc.contributor.localIdA03490-
dc.relation.journalcodeJ01320-
dc.identifier.eissn1751-7176-
dc.identifier.pmid32951315-
dc.subject.keywordblood pressure-
dc.subject.keyworddiscriminatory ability-
dc.subject.keywordhypertension-
dc.subject.keywordmortality-
dc.contributor.alternativeNameSon, Da‐Hye-
dc.contributor.affiliatedAuthor손다혜-
dc.contributor.affiliatedAuthor이지원-
dc.contributor.affiliatedAuthor이지원-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor장혁재-
dc.contributor.affiliatedAuthor장혁재-
dc.citation.volume22-
dc.citation.number11-
dc.citation.startPage2035-
dc.citation.endPage2043-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL HYPERTENSION, Vol.22(11) : 2035-2043, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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