Cited 3 times in
Is there association between statin usage and contrast-associated acute kidney injury after intravenous administration of iodine-based contrast media in enhanced computed tomography?
DC Field | Value | Language |
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dc.contributor.author | 김명진 | - |
dc.contributor.author | 박미숙 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 정용은 | - |
dc.contributor.author | 최진영 | - |
dc.date.accessioned | 2020-12-01T17:17:51Z | - |
dc.date.available | 2020-12-01T17:17:51Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180208 | - |
dc.description.abstract | Objectives: Contrast-induced acute kidney injury (CI-AKI) is one of the leading causes of new-onset renal failure in hospitalized patients. Statin has been evaluated for its protective effect against CI-AKI but rarely in patients receiving intravenous (IV) administrations of iodine-based contrast media for enhanced computed tomography (CT). Methods: In total, 12,371 patients who underwent contrast-enhanced abdominopelvic CT were retrospectively reviewed and stratified into statin users and statin nonusers. Subgroup analyses comparing high-intensity statins with low- to moderate-intensity statins were conducted within statin users and similar comparisons were performed within statin users stratified based on baseline eGFR. Results: Overall, CI-AKI events did not occur less in statin users compared with non-statin users (p = 0.342). Within statin users, CI-AKI events did not decrease in high-intensity statin users compared with low- to moderate-intensity statin users (p = 0.355). Moreover, no significant difference in CI-AKI events was found between high-intensity statin users and low- to moderate-intensity statin users even after stratifying the patients with baseline eGFR. Conclusions: Collectively, statin was not significantly associated with the risk of CI-AKI events in patients undergoing contrast-enhanced abdominopelvic CT and high-intensity statins did not show significant association with CI-AKI over low- to moderate-intensity statins in the subgroup analysis. Key points: • Statin is not associated with risk of CI-AKI events in patients undergoing intravenous administration of contrast-enhanced CT. • CI-AKI incidence among high-intensity statin users was not significantly different from that of low- to moderate-intensity statin users. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer International | - |
dc.relation.isPartOf | EUROPEAN RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Is there association between statin usage and contrast-associated acute kidney injury after intravenous administration of iodine-based contrast media in enhanced computed tomography? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Jae Hyon Park | - |
dc.contributor.googleauthor | Hye Jung Shin | - |
dc.contributor.googleauthor | Jin-Young Choi | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Hyung Jung Oh | - |
dc.contributor.googleauthor | Yong Eun Chung | - |
dc.identifier.doi | 10.1007/s00330-020-06897-4 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A01463 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A03662 | - |
dc.contributor.localId | A04200 | - |
dc.relation.journalcode | J00851 | - |
dc.identifier.eissn | 1432-1084 | - |
dc.identifier.pmid | 32399711 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs00330-020-06897-4 | - |
dc.subject.keyword | Contrast material | - |
dc.subject.keyword | Glomerular filtration rate | - |
dc.subject.keyword | Incidence | - |
dc.subject.keyword | Multidetector computed tomography | - |
dc.subject.keyword | Renal insufficiency | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | 김명진 | - |
dc.contributor.affiliatedAuthor | 박미숙 | - |
dc.contributor.affiliatedAuthor | 임준석 | - |
dc.contributor.affiliatedAuthor | 정용은 | - |
dc.contributor.affiliatedAuthor | 최진영 | - |
dc.citation.volume | 30 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 5261 | - |
dc.citation.endPage | 5271 | - |
dc.identifier.bibliographicCitation | EUROPEAN RADIOLOGY, Vol.30(10) : 5261-5271, 2020-10 | - |
dc.identifier.rimsid | 67362 | - |
dc.type.rims | ART | - |
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