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Effect of image quality fluctuations on the repeatability of thickness measurements in swept-source optical coherence tomography

DC FieldValueLanguage
dc.contributor.author김찬윤-
dc.contributor.author배형원-
dc.contributor.author성공제-
dc.contributor.author이상엽-
dc.contributor.author이혜선-
dc.date.accessioned2020-12-01T16:49:12Z-
dc.date.available2020-12-01T16:49:12Z-
dc.date.issued2020-08-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179991-
dc.description.abstractThis study investigated the effect of image quality fluctuations on the repeatability of thickness measurements of the peripapillary retinal nerve fibre (PP-RNFL) and ganglion cell-inner plexiform (GC-IPL) layers using swept-source optical coherence tomography (SS-OCT). Three consecutive OCT scans each were performed on 56 healthy subject. Finally, 168 SS-OCT results were analysed. Based on the tertile values of the mean absolute difference of image quality score, all subjects were divided into the following three groups-low-(LIQD), moderate-(MIQD), and high-(HIQD) image quality score difference groups. A linear mixed model and intraclass correlation coefficients (ICCs) were used for analyses. Despite high ICC values (> 0.9), several sectors showed significant differences in the ICC values in intergroup comparisons. For LIQD-HIQD and MIQD-HIQD, most PP-RNFL sectors showed significant differences. For GC-IPL sectors, the LIQD-HIQD comparison showed significant differences in the temporosuperior (p = 0.012), inferior (p < .001), and temporoinferior (p = 0.042) sectors. Significant differences existed in the average GC-IPL (p = 0.009), nasoinferior (p = 0.035), and inferior GC-IPL sectors (p < .001) for MIQD-HIQD comparison. With higher image quality fluctuations, the repeatability of SS-OCT decreased in several sectors, which are considered clinically relevant in evaluating glaucoma status. Therefore, maintaining high-quality image status is essential to enhance the reliability of SS-OCT.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleEffect of image quality fluctuations on the repeatability of thickness measurements in swept-source optical coherence tomography-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학교실)-
dc.contributor.googleauthorHeon Yang-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorHyoung Won Bae-
dc.contributor.googleauthorGong Je Seong-
dc.contributor.googleauthorChan Yun Kim-
dc.contributor.googleauthorSang Yeop Lee-
dc.identifier.doi10.1038/s41598-020-70852-y-
dc.contributor.localIdA01035-
dc.contributor.localIdA01814-
dc.contributor.localIdA01814-
dc.contributor.localIdA01946-
dc.contributor.localIdA01946-
dc.contributor.localIdA02820-
dc.contributor.localIdA02820-
dc.contributor.localIdA03312-
dc.contributor.localIdA03312-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid32807868-
dc.contributor.alternativeNameKim, Chan Yun-
dc.contributor.affiliatedAuthor김찬윤-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor이혜선-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPage13897-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.10(1) : 13897, 2020-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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