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Ultrasonography surveillance in papillary thyroid carcinoma patients after total thyroidectomy according to dynamic risk stratification

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dc.contributor.author윤정현-
dc.contributor.author윤지영-
dc.contributor.author박영진-
dc.contributor.author문희정-
dc.contributor.author곽진영-
dc.contributor.author김은경-
dc.contributor.author이잔디-
dc.date.accessioned2020-10-04T16:49:56Z-
dc.date.available2020-10-04T16:49:56Z-
dc.date.issued2020-08-
dc.identifier.issn1355-008X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179688-
dc.description.abstractPurpose: To investigate the role of neck US surveillance in patients with papillary thyroid carcinoma (PTC) after total thyroidectomy according to dynamic risk stratification (DRS) based on response to initial therapy. Methods: This retrospective study included 812 patients with PTC who underwent total thyroidectomy with prophylactic central neck dissection from January 2003 through February 2007. The relative risk of recurrence/persistence according to DRS was evaluated with the multivariable Cox regression proportional hazard model. Results: There were 132 men and 680 women. The mean age at surgery was 45.2 years. Postoperative US was used for DRS. According to DRS, 676 patients had excellent response, 78 indeterminate response, 40 biochemical incomplete response, and 18 structural incomplete response to initial therapy. Neck US was performed during follow-up and detected locoregional recurrences in 21 patients (2.6%): 12 with excellent response, 2 with biochemical incomplete response, and 7 with structural incomplete response according to DRS. Only 1 patient (0.1%) with excellent response had a locoregional recurrence that exceeded 8 mm in its shortest diameter, which is the size cut-off for diagnostic US fine-needle aspiration in suspicious lymph nodes. This patient did not develop biochemical abnormalities during follow-up. Conclusions: Postoperative neck US surveillance after total thyroidectomy with prophylactic central neck dissection is not essential in PTC patients who show excellent response to initial therapy. Future studies are needed to verify the role of US surveillance in patients who receive variable degrees of treatments.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherHumana Press-
dc.relation.isPartOfENDOCRINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleUltrasonography surveillance in papillary thyroid carcinoma patients after total thyroidectomy according to dynamic risk stratification-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorJiyoung Yoon-
dc.contributor.googleauthorJung Hyun Yoon-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorJandee Lee-
dc.contributor.googleauthorEun-Kyung Kim-
dc.contributor.googleauthorHee Jung Moon-
dc.contributor.googleauthorVivian Youngjean Park-
dc.contributor.googleauthorJin Young Kwak-
dc.identifier.doi10.1007/s12020-020-02347-9-
dc.contributor.localIdA02595-
dc.contributor.localIdA05730-
dc.contributor.localIdA01572-
dc.contributor.localIdA01397-
dc.contributor.localIdA00182-
dc.contributor.localIdA00801-
dc.contributor.localIdA03066-
dc.relation.journalcodeJ00768-
dc.identifier.eissn1559-0100-
dc.identifier.pmid32449109-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs12020-020-02347-9-
dc.subject.keywordBiopsy, fine needle-
dc.subject.keywordGuideline-
dc.subject.keywordThyroid cancer, papillary-
dc.subject.keywordThyroidectomy-
dc.subject.keywordUltrasonography-
dc.contributor.alternativeNameYoon, Jung Hyun-
dc.contributor.affiliatedAuthor윤정현-
dc.contributor.affiliatedAuthor윤지영-
dc.contributor.affiliatedAuthor박영진-
dc.contributor.affiliatedAuthor문희정-
dc.contributor.affiliatedAuthor곽진영-
dc.contributor.affiliatedAuthor김은경-
dc.contributor.affiliatedAuthor이잔디-
dc.citation.volume69-
dc.citation.number2-
dc.citation.startPage347-
dc.citation.endPage357-
dc.identifier.bibliographicCitationENDOCRINE, Vol.69(2) : 347-357, 2020-08-
dc.identifier.rimsid67341-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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