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Magnetic resonance image-based tomotherapy planning for prostate cancer

Authors
 Sang Hoon Jung  ;  Jinsung Kim  ;  Yoonsun Chung  ;  Bilgin Keserci  ;  Hongryull Pyo  ;  Hee Chul Park  ;  Won Park 
Citation
 RADIATION ONCOLOGY JOURNAL, Vol.38(1) : 52-59, 2020-03 
Journal Title
RADIATION ONCOLOGY JOURNAL
ISSN
 2234-1900 
Issue Date
2020-03
Keywords
Helical Tomotherapy ; Magnetic Resonance Imaging ; Prostatic Neopla는
Abstract
Purpose: To evaluate and compare the feasibilities of magnetic resonance (MR) image-based planning using synthetic computed tomography (sCT) versus CT (pCT)-based planning in helical tomotherapy for prostate cancer.

Materials and methods: A retrospective evaluation was performed in 16 patients with prostate cancer who had been treated with helical tomotherapy. MR images were acquired using a dedicated therapy sequence; sCT images were generated using magnetic resonance for calculating attenuation (MRCAT). The three-dimensional dose distribution according to sCT was recalculated using a previously optimized plan and was compared with the doses calculated using pCT.

Results: The mean planning target volume doses calculated by sCT and pCT differed by 0.65% ± 1.11% (p = 0.03). Three-dimensional gamma analysis at a 2%/2 mm dose difference/distance to agreement yielded a pass rate of 0.976 (range, 0.658 to 0.986).

Conclusion: The dose distribution results obtained using tomotherapy from MR-only simulations were in good agreement with the dose distribution results from simulation CT, with mean dose differences of less than 1% for target volume and normal organs in patients with prostate cancer.
Files in This Item:
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DOI
10.3857/roj.2020.00101
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jinsung(김진성) ORCID logo https://orcid.org/0000-0003-1415-6471
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/179056
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