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A rare case of chronic nonbacterial osteomyelitis of the mandible in a young adult male

Authors
 Yesel Kim  ;  Jinhyuk Choi  ;  Hoi-In Jung  ;  Jeong-Kui Ku 
Citation
 Oral Biology Research (구강생물학연구), Vol.44(1) : 51-60, 2020-01 
Journal Title
Oral Biology Research(구강생물학연구)
ISSN
 1226-928X 
Issue Date
2020-01
Keywords
Chronic recurrent multifocal osteomyelitis ; Magnetic resonance imaging ; Mandible ; Oral surgery
Abstract
Chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis, is a rare disease of unknown
etiology mainly affecting girls with a mean age of 10 years. The disease is characterized by nonbacterial osteolytic lesions and swelling
of the adjacent soft tissues and has nonstandard treatment protocols. Unifocal CNO typically involves the mandible. Mandibular CNO
is difficult to differentiate from bacterial osteomyelitis because of its similar radiographic profile and clinical symptoms. Therefore,
magnetic resonance imaging (MRI) should be considered if infectious osteomyelitis has not been diagnosed by laboratory examination.
Our patient was a young adult man with mandibular CNO presented with atypical bone fragments on MRI. Clinical symptoms
improved within 3 days after surgical intervention to remove the fragments and treatment with a nonsteroidal anti-inflammatory drug
(NSAID). NSAID therapy was discontinued at postoperative day 20, and the patient has experienced no recurrences at 5 months after
surgery.
Files in This Item:
T202002273.pdf Download
DOI
10.21851/obr.44.01.202003.51
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Preventive Dentistry and Public Oral Health (예방치과학교실) > 1. Journal Papers
Yonsei Authors
Jung, Hoi In(정회인) ORCID logo https://orcid.org/0000-0002-1978-6926
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178968
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