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Early onset polymyalgia rheumatica: two rare cases under age of 50

Authors
 Jinyoung Park  ;  Duk Hyun Sung 
Citation
 SKELETAL RADIOLOGY, Vol.46(6) : 837-840, 2017-06 
Journal Title
 SKELETAL RADIOLOGY 
ISSN
 0364-2348 
Issue Date
2017-06
Keywords
18F-Fluorodeoxyglucose ; Polymyalgia rheumatica ; Positron-emission tomography ; Rheumatoid arthritis ; Spondylarthropathies
Abstract
Polymyalgia rheumatica (PMR) is almost an exclusive disease of adults over the age of 50, and only a few cases have been reported. Two 46-year-old females visited our locomotor pain clinic with multiple joint pain with increased acute phase reactants. Rheumatologic markers, and HLA-B27 were checked. Serum protein electrophoresis and serum immunofixation electrophoresis, imaging studies including plane image, sonography, and magnetic resonance image was done. 18F-Fludeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) showed characteristic findings of PMR, without evidences of sacroiliitis. Since PMR can develop in mid 40s, a high index of suspicion is necessary in younger patients presenting the bilateral pain in shoulders, hips, and back, with elevated acute phase reactants. Furthermore, in addition to the previous case reports, FDG-PET/CT is helpful in making early differential diagnosis of PMR in patients under the age of 50. Here we present two cases of PMR onset in the mid-40s emphasizing the importance of diagnostic imaging for early differential diagnosis in PMR.
Full Text
https://link.springer.com/article/10.1007/s00256-017-2618-5
DOI
10.1007/s00256-017-2618-5
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Park, Jinyoung(박진영) ORCID logo https://orcid.org/0000-0003-4042-9779
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178367
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