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흡연 및 비흡연 정신분열증 환자간의 인지 기능과 치료 반응의 차이

Other Titles
 Differences of Cognitive Function and Treatment Response between Smoking and Non-smoking Schizophrenic Patients 
Authors
 남궁기  ;  민성길  ;  이희상  ;  조현상  ;  김세주 
Citation
 Journal of the Korean Neuropsychiatric Association (신경정신의학), Vol.36(4) : 630-642, 1997 
Journal Title
 Journal of the Korean Neuropsychiatric Association (신경정신의학) 
ISSN
 1015-4817 
Issue Date
1997
Abstract
Objectives:The purpose of this study was to examine the differences of past histories, current symptoms, treatment responses and cognitive functions between smoking and non-smoking schizophrenic patients. Methods:The subjects were composed of 67 schizophrenic patients including 36 smokers and 31 non-smokers. They were examined by psychiatric history checklist, Simpson and Angus’s rating scale for extrapyramidal side effects, positive & negative syndromes scale(PANSS), global assessment scale(GAS), and Vienna test including Standard Progressive Matrices(SPM), Cognitron, and Flicker Fusion Analyzer(FFA) Results:The results were as follows: 1) Although the duration of illness of smokers was longer than that of non-smokers, the smokers had significantly higher score of GAS and significantly lower score of PANSS than non-smokers at admission. 2) With effects of age and duration of illness controlled, there were no differences of mean dosage of neuroleptics, extrapyramidal side effects, PANSS improvement rate and GAS improvement rate between both groups. 3) With effects of age, duration of illness, and total PANSS score controlled, there were no differences of score of SPM, cognitron, and FFA. 4) In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes, with effects of age and duration of illness controlled. Conclusions:In schizophrenic patients, smokers had less severe symptoms than non-smokers. In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes. But smokers were not proven to have receivd higher dosage of neuroleptics, to have lower extrapyramidal side effects, or to have less severe impairment of cognitive function.
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Se Joo(김세주) ORCID logo https://orcid.org/0000-0002-5438-8210
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178006
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